Elevated audiovisual temporal interaction in patients with migraine without aura

Weiping Yang, Bingqian Chu, Jiajia Yang, Yinghua Yu, Jinglong Wu, Shengyuan Yu

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Background: Photophobia and phonophobia are the most prominent symptoms in patients with migraine without aura. Hypersensitivity to visual stimuli can lead to greater hypersensitivity to auditory stimuli, which suggests that the interaction between visual and auditory stimuli may play an important role in the pathogenesis of migraine. However, audiovisual temporal interactions in migraine have not been well studied. Therefore, our aim was to examine auditory and visual interactions in migraine. Methods: In this study, visual, auditory, and audiovisual stimuli with different temporal intervals between the visual and auditory stimuli were randomly presented to the left or right hemispace. During this time, the participants were asked to respond promptly to target stimuli. We used cumulative distribution functions to analyze the response times as a measure of audiovisual integration. Results: Our results showed that audiovisual integration was significantly elevated in the migraineurs compared with the normal controls (p < 0.05); however, audiovisual suppression was weaker in the migraineurs compared with the normal controls (p < 0.05). Conclusions: Our findings further objectively support the notion that migraineurs without aura are hypersensitive to external visual and auditory stimuli. Our study offers a new quantitative and objective method to evaluate hypersensitivity to audio-visual stimuli in patients with migraine.

Original languageEnglish
Article number44
Pages (from-to)1-10
Number of pages10
JournalJournal of Headache and Pain
Volume15
Issue number1
DOIs
Publication statusPublished - Dec 1 2014

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Keywords

  • Attention
  • Audiovisual integration
  • Hypersensitivity
  • Migraine
  • Race model

ASJC Scopus subject areas

  • Clinical Neurology
  • Anesthesiology and Pain Medicine

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