Elevated audiovisual temporal interaction in patients with migraine without aura

Weiping Yang, Bingqian Chu, Jiajia Yang, Yinghua Yu, Jinglong Wu, Shengyuan Yu

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Background: Photophobia and phonophobia are the most prominent symptoms in patients with migraine without aura. Hypersensitivity to visual stimuli can lead to greater hypersensitivity to auditory stimuli, which suggests that the interaction between visual and auditory stimuli may play an important role in the pathogenesis of migraine. However, audiovisual temporal interactions in migraine have not been well studied. Therefore, our aim was to examine auditory and visual interactions in migraine. Methods: In this study, visual, auditory, and audiovisual stimuli with different temporal intervals between the visual and auditory stimuli were randomly presented to the left or right hemispace. During this time, the participants were asked to respond promptly to target stimuli. We used cumulative distribution functions to analyze the response times as a measure of audiovisual integration. Results: Our results showed that audiovisual integration was significantly elevated in the migraineurs compared with the normal controls (p <0.05); however, audiovisual suppression was weaker in the migraineurs compared with the normal controls (p <0.05). Conclusions: Our findings further objectively support the notion that migraineurs without aura are hypersensitive to external visual and auditory stimuli. Our study offers a new quantitative and objective method to evaluate hypersensitivity to audio-visual stimuli in patients with migraine.

Original languageEnglish
Article number44
Pages (from-to)1-10
Number of pages10
JournalThe journal of headache and pain
Volume15
Issue number1
DOIs
Publication statusPublished - Dec 1 2014

Fingerprint

Migraine without Aura
Migraine Disorders
Hypersensitivity
Hyperacusis
Photophobia
Reaction Time
Epilepsy

Keywords

  • Attention
  • Audiovisual integration
  • Hypersensitivity
  • Migraine
  • Race model

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine
  • Clinical Neurology

Cite this

Elevated audiovisual temporal interaction in patients with migraine without aura. / Yang, Weiping; Chu, Bingqian; Yang, Jiajia; Yu, Yinghua; Wu, Jinglong; Yu, Shengyuan.

In: The journal of headache and pain, Vol. 15, No. 1, 44, 01.12.2014, p. 1-10.

Research output: Contribution to journalArticle

Yang, Weiping ; Chu, Bingqian ; Yang, Jiajia ; Yu, Yinghua ; Wu, Jinglong ; Yu, Shengyuan. / Elevated audiovisual temporal interaction in patients with migraine without aura. In: The journal of headache and pain. 2014 ; Vol. 15, No. 1. pp. 1-10.
@article{110c2b3d68254d01b7fb48cf4bd8efe0,
title = "Elevated audiovisual temporal interaction in patients with migraine without aura",
abstract = "Background: Photophobia and phonophobia are the most prominent symptoms in patients with migraine without aura. Hypersensitivity to visual stimuli can lead to greater hypersensitivity to auditory stimuli, which suggests that the interaction between visual and auditory stimuli may play an important role in the pathogenesis of migraine. However, audiovisual temporal interactions in migraine have not been well studied. Therefore, our aim was to examine auditory and visual interactions in migraine. Methods: In this study, visual, auditory, and audiovisual stimuli with different temporal intervals between the visual and auditory stimuli were randomly presented to the left or right hemispace. During this time, the participants were asked to respond promptly to target stimuli. We used cumulative distribution functions to analyze the response times as a measure of audiovisual integration. Results: Our results showed that audiovisual integration was significantly elevated in the migraineurs compared with the normal controls (p <0.05); however, audiovisual suppression was weaker in the migraineurs compared with the normal controls (p <0.05). Conclusions: Our findings further objectively support the notion that migraineurs without aura are hypersensitive to external visual and auditory stimuli. Our study offers a new quantitative and objective method to evaluate hypersensitivity to audio-visual stimuli in patients with migraine.",
keywords = "Attention, Audiovisual integration, Hypersensitivity, Migraine, Race model",
author = "Weiping Yang and Bingqian Chu and Jiajia Yang and Yinghua Yu and Jinglong Wu and Shengyuan Yu",
year = "2014",
month = "12",
day = "1",
doi = "10.1186/1129-2377-15-44",
language = "English",
volume = "15",
pages = "1--10",
journal = "Journal of Headache and Pain",
issn = "1129-2369",
publisher = "Springer-Verlag Italia",
number = "1",

}

TY - JOUR

T1 - Elevated audiovisual temporal interaction in patients with migraine without aura

AU - Yang, Weiping

AU - Chu, Bingqian

AU - Yang, Jiajia

AU - Yu, Yinghua

AU - Wu, Jinglong

AU - Yu, Shengyuan

PY - 2014/12/1

Y1 - 2014/12/1

N2 - Background: Photophobia and phonophobia are the most prominent symptoms in patients with migraine without aura. Hypersensitivity to visual stimuli can lead to greater hypersensitivity to auditory stimuli, which suggests that the interaction between visual and auditory stimuli may play an important role in the pathogenesis of migraine. However, audiovisual temporal interactions in migraine have not been well studied. Therefore, our aim was to examine auditory and visual interactions in migraine. Methods: In this study, visual, auditory, and audiovisual stimuli with different temporal intervals between the visual and auditory stimuli were randomly presented to the left or right hemispace. During this time, the participants were asked to respond promptly to target stimuli. We used cumulative distribution functions to analyze the response times as a measure of audiovisual integration. Results: Our results showed that audiovisual integration was significantly elevated in the migraineurs compared with the normal controls (p <0.05); however, audiovisual suppression was weaker in the migraineurs compared with the normal controls (p <0.05). Conclusions: Our findings further objectively support the notion that migraineurs without aura are hypersensitive to external visual and auditory stimuli. Our study offers a new quantitative and objective method to evaluate hypersensitivity to audio-visual stimuli in patients with migraine.

AB - Background: Photophobia and phonophobia are the most prominent symptoms in patients with migraine without aura. Hypersensitivity to visual stimuli can lead to greater hypersensitivity to auditory stimuli, which suggests that the interaction between visual and auditory stimuli may play an important role in the pathogenesis of migraine. However, audiovisual temporal interactions in migraine have not been well studied. Therefore, our aim was to examine auditory and visual interactions in migraine. Methods: In this study, visual, auditory, and audiovisual stimuli with different temporal intervals between the visual and auditory stimuli were randomly presented to the left or right hemispace. During this time, the participants were asked to respond promptly to target stimuli. We used cumulative distribution functions to analyze the response times as a measure of audiovisual integration. Results: Our results showed that audiovisual integration was significantly elevated in the migraineurs compared with the normal controls (p <0.05); however, audiovisual suppression was weaker in the migraineurs compared with the normal controls (p <0.05). Conclusions: Our findings further objectively support the notion that migraineurs without aura are hypersensitive to external visual and auditory stimuli. Our study offers a new quantitative and objective method to evaluate hypersensitivity to audio-visual stimuli in patients with migraine.

KW - Attention

KW - Audiovisual integration

KW - Hypersensitivity

KW - Migraine

KW - Race model

UR - http://www.scopus.com/inward/record.url?scp=84957538357&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84957538357&partnerID=8YFLogxK

U2 - 10.1186/1129-2377-15-44

DO - 10.1186/1129-2377-15-44

M3 - Article

C2 - 24961903

AN - SCOPUS:84937511586

VL - 15

SP - 1

EP - 10

JO - Journal of Headache and Pain

JF - Journal of Headache and Pain

SN - 1129-2369

IS - 1

M1 - 44

ER -