Electrochemical Synthesis of Thienoacene Derivatives: Transition-Metal-Free Dehydrogenative C−S Coupling Promoted by a Halogen Mediator

Koichi Mitsudo, Ren Matsuo, Toki Yonezawa, Haruka Inoue, Hiroki Mandai, Seiji Suga

Research output: Contribution to journalArticle


The first electrochemical dehydrogenative C−S bond formation leading to thienoacene derivatives is described. Several thienoacene derivatives were synthesized by dehydrogenative C−H/S−H coupling. The addition of nBu4NBr, which catalytically promoted the reaction as a halogen mediator, was essential.

Original languageEnglish
Pages (from-to)7803-7807
Number of pages5
JournalAngewandte Chemie - International Edition
Issue number20
Publication statusPublished - May 11 2020



  • cross-coupling
  • cyclization
  • electrochemistry
  • heterocycles
  • synthetic methods

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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