EIN2, a bifunctional transducer of ethylene and stress responses in Arabidopsis

Jose M. Alonso, Takashi Hirayama, Gregg Roman, Saeid Nourizadeh, Joseph R. Ecker

Research output: Contribution to journalArticle

816 Citations (Scopus)

Abstract

Ethylene regulates plant growth, development, and responsiveness to a variety of stresses. Cloning of the Arabidopsis EIN2 gene identifies a central component of the ethylene signalng pathway. The amino-terminal integral membrane domain of EIN2 Shows similarity to the disease-related Nramp family of metalion transporters. Expression of the EIN2 CEND is Sufficient to constitutively activate ethylene responses and restores responsiveness to jasmonic acid and paraquat-induced oxygen radicals to mutant plants. EIN2 is thus recognized as a molecular link between previously distinct hormone response pathways. Plants may use a combinatorial mechanism for assessing various stresses by enlisting a common set of signaling molecules.

Original languageEnglish
Pages (from-to)2148-2152
Number of pages5
JournalScience
Volume284
Issue number5423
DOIs
Publication statusPublished - Jun 25 1999
Externally publishedYes

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Transducers
Arabidopsis
Paraquat
Plant Development
Growth and Development
Organism Cloning
Reactive Oxygen Species
Hormones
Membranes
Genes
ethylene

ASJC Scopus subject areas

  • General

Cite this

EIN2, a bifunctional transducer of ethylene and stress responses in Arabidopsis. / Alonso, Jose M.; Hirayama, Takashi; Roman, Gregg; Nourizadeh, Saeid; Ecker, Joseph R.

In: Science, Vol. 284, No. 5423, 25.06.1999, p. 2148-2152.

Research output: Contribution to journalArticle

Alonso, Jose M. ; Hirayama, Takashi ; Roman, Gregg ; Nourizadeh, Saeid ; Ecker, Joseph R. / EIN2, a bifunctional transducer of ethylene and stress responses in Arabidopsis. In: Science. 1999 ; Vol. 284, No. 5423. pp. 2148-2152.
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