Efficient asymmetric synthesis of (S)-2-ethylphenylpropanoic acid derivative, a selective agonist for human peroxisome proliferator-activated receptor alpha

Masahiro Nomura, Takahiro Tanase, Hiroyuki Miyachi

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

An optically active phenylpropanoic acid derivative, a selective agonist for human peroxisome proliferator-activated receptor alpha, was efficiently prepared in high optical purity by using Evans chiral oxazolidinone technique as a key step.

Original languageEnglish
Pages (from-to)2101-2104
Number of pages4
JournalBioorganic and Medicinal Chemistry Letters
Volume12
Issue number16
DOIs
Publication statusPublished - Aug 19 2002

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

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