Effects of vitamin D receptor gene polymorphisms on low-resistance training using exercise machines

The 'power rehabilitation' program

Shin Ichiro Murakami, Takemi Otsuki, Megumi Maeda, Yoshie Miura, Seiko Morii, Kenji Kiyokane, Shin Ichi Hayakawa, Atsushi Maeda, Takayo Imakawa, Shunpei Harada, Torataro Handa, Yasumitsu Nishimura, Shuko Murakami, Naoko Kumagai, Hiroaki Hayashi, Ying Chen, Shin Ichiro Suemori, Yumiko Fukushima, Seikoh Nishida, Keisuke Fukushima

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The enhancement and promotion of health is necessary to maintain the quality of life (QOL) of the aged population in developed nations such as Japan where the number of elderly has been increasing rapidly. For this purpose, low-resistance training using exercise machines ('Power Rehabilitation') has been established as a rehabilitation program. To investigate the individual factors which influence the effects of 'Power Rehabilitation', single nucleotide polymorphisms (SNPs) in the vitamin D receptor (VDR) gene and the ciliary neurotrophic factor (CNTF) gene were analyzed, and the relationship between SNP patterns and the effects of 'Power Rehabilitation' was evaluated. 'Power Rehabilitation' had an effect on the physiological functions involved in the activities of daily life (ADL) rather than muscle strength and size. In addition, certain SNP patterns showed better improvement of parameters associated with the effects of 'Power Rehabilitation' as analyzed by comparison between SNP patterns and factor analysis. Large scale analyses are required to ensure this tendency and to discover individual factors which may help to promote the health and QOL of the aged population.

Original languageEnglish
Pages (from-to)81-88
Number of pages8
JournalInternational Journal of Molecular Medicine
Volume23
Issue number1
DOIs
Publication statusPublished - 2009
Externally publishedYes

Fingerprint

Calcitriol Receptors
Resistance Training
Rehabilitation
Exercise
Single Nucleotide Polymorphism
Genes
Quality of Life
Ciliary Neurotrophic Factor
Muscle Strength
Health Promotion
Developed Countries
Population
Statistical Factor Analysis
Japan
Health

Keywords

  • Low-resistance training
  • Rehabilitation
  • Single nucleotide polymorphism
  • Vitmin D receptor

ASJC Scopus subject areas

  • Genetics

Cite this

Effects of vitamin D receptor gene polymorphisms on low-resistance training using exercise machines : The 'power rehabilitation' program. / Murakami, Shin Ichiro; Otsuki, Takemi; Maeda, Megumi; Miura, Yoshie; Morii, Seiko; Kiyokane, Kenji; Hayakawa, Shin Ichi; Maeda, Atsushi; Imakawa, Takayo; Harada, Shunpei; Handa, Torataro; Nishimura, Yasumitsu; Murakami, Shuko; Kumagai, Naoko; Hayashi, Hiroaki; Chen, Ying; Suemori, Shin Ichiro; Fukushima, Yumiko; Nishida, Seikoh; Fukushima, Keisuke.

In: International Journal of Molecular Medicine, Vol. 23, No. 1, 2009, p. 81-88.

Research output: Contribution to journalArticle

Murakami, SI, Otsuki, T, Maeda, M, Miura, Y, Morii, S, Kiyokane, K, Hayakawa, SI, Maeda, A, Imakawa, T, Harada, S, Handa, T, Nishimura, Y, Murakami, S, Kumagai, N, Hayashi, H, Chen, Y, Suemori, SI, Fukushima, Y, Nishida, S & Fukushima, K 2009, 'Effects of vitamin D receptor gene polymorphisms on low-resistance training using exercise machines: The 'power rehabilitation' program', International Journal of Molecular Medicine, vol. 23, no. 1, pp. 81-88. https://doi.org/10.3892/ijmm_00000104
Murakami, Shin Ichiro ; Otsuki, Takemi ; Maeda, Megumi ; Miura, Yoshie ; Morii, Seiko ; Kiyokane, Kenji ; Hayakawa, Shin Ichi ; Maeda, Atsushi ; Imakawa, Takayo ; Harada, Shunpei ; Handa, Torataro ; Nishimura, Yasumitsu ; Murakami, Shuko ; Kumagai, Naoko ; Hayashi, Hiroaki ; Chen, Ying ; Suemori, Shin Ichiro ; Fukushima, Yumiko ; Nishida, Seikoh ; Fukushima, Keisuke. / Effects of vitamin D receptor gene polymorphisms on low-resistance training using exercise machines : The 'power rehabilitation' program. In: International Journal of Molecular Medicine. 2009 ; Vol. 23, No. 1. pp. 81-88.
@article{a64953bdfad140dd9af8eb2a65108d4c,
title = "Effects of vitamin D receptor gene polymorphisms on low-resistance training using exercise machines: The 'power rehabilitation' program",
abstract = "The enhancement and promotion of health is necessary to maintain the quality of life (QOL) of the aged population in developed nations such as Japan where the number of elderly has been increasing rapidly. For this purpose, low-resistance training using exercise machines ('Power Rehabilitation') has been established as a rehabilitation program. To investigate the individual factors which influence the effects of 'Power Rehabilitation', single nucleotide polymorphisms (SNPs) in the vitamin D receptor (VDR) gene and the ciliary neurotrophic factor (CNTF) gene were analyzed, and the relationship between SNP patterns and the effects of 'Power Rehabilitation' was evaluated. 'Power Rehabilitation' had an effect on the physiological functions involved in the activities of daily life (ADL) rather than muscle strength and size. In addition, certain SNP patterns showed better improvement of parameters associated with the effects of 'Power Rehabilitation' as analyzed by comparison between SNP patterns and factor analysis. Large scale analyses are required to ensure this tendency and to discover individual factors which may help to promote the health and QOL of the aged population.",
keywords = "Low-resistance training, Rehabilitation, Single nucleotide polymorphism, Vitmin D receptor",
author = "Murakami, {Shin Ichiro} and Takemi Otsuki and Megumi Maeda and Yoshie Miura and Seiko Morii and Kenji Kiyokane and Hayakawa, {Shin Ichi} and Atsushi Maeda and Takayo Imakawa and Shunpei Harada and Torataro Handa and Yasumitsu Nishimura and Shuko Murakami and Naoko Kumagai and Hiroaki Hayashi and Ying Chen and Suemori, {Shin Ichiro} and Yumiko Fukushima and Seikoh Nishida and Keisuke Fukushima",
year = "2009",
doi = "10.3892/ijmm_00000104",
language = "English",
volume = "23",
pages = "81--88",
journal = "International Journal of Molecular Medicine",
issn = "1107-3756",
publisher = "Spandidos Publications",
number = "1",

}

TY - JOUR

T1 - Effects of vitamin D receptor gene polymorphisms on low-resistance training using exercise machines

T2 - The 'power rehabilitation' program

AU - Murakami, Shin Ichiro

AU - Otsuki, Takemi

AU - Maeda, Megumi

AU - Miura, Yoshie

AU - Morii, Seiko

AU - Kiyokane, Kenji

AU - Hayakawa, Shin Ichi

AU - Maeda, Atsushi

AU - Imakawa, Takayo

AU - Harada, Shunpei

AU - Handa, Torataro

AU - Nishimura, Yasumitsu

AU - Murakami, Shuko

AU - Kumagai, Naoko

AU - Hayashi, Hiroaki

AU - Chen, Ying

AU - Suemori, Shin Ichiro

AU - Fukushima, Yumiko

AU - Nishida, Seikoh

AU - Fukushima, Keisuke

PY - 2009

Y1 - 2009

N2 - The enhancement and promotion of health is necessary to maintain the quality of life (QOL) of the aged population in developed nations such as Japan where the number of elderly has been increasing rapidly. For this purpose, low-resistance training using exercise machines ('Power Rehabilitation') has been established as a rehabilitation program. To investigate the individual factors which influence the effects of 'Power Rehabilitation', single nucleotide polymorphisms (SNPs) in the vitamin D receptor (VDR) gene and the ciliary neurotrophic factor (CNTF) gene were analyzed, and the relationship between SNP patterns and the effects of 'Power Rehabilitation' was evaluated. 'Power Rehabilitation' had an effect on the physiological functions involved in the activities of daily life (ADL) rather than muscle strength and size. In addition, certain SNP patterns showed better improvement of parameters associated with the effects of 'Power Rehabilitation' as analyzed by comparison between SNP patterns and factor analysis. Large scale analyses are required to ensure this tendency and to discover individual factors which may help to promote the health and QOL of the aged population.

AB - The enhancement and promotion of health is necessary to maintain the quality of life (QOL) of the aged population in developed nations such as Japan where the number of elderly has been increasing rapidly. For this purpose, low-resistance training using exercise machines ('Power Rehabilitation') has been established as a rehabilitation program. To investigate the individual factors which influence the effects of 'Power Rehabilitation', single nucleotide polymorphisms (SNPs) in the vitamin D receptor (VDR) gene and the ciliary neurotrophic factor (CNTF) gene were analyzed, and the relationship between SNP patterns and the effects of 'Power Rehabilitation' was evaluated. 'Power Rehabilitation' had an effect on the physiological functions involved in the activities of daily life (ADL) rather than muscle strength and size. In addition, certain SNP patterns showed better improvement of parameters associated with the effects of 'Power Rehabilitation' as analyzed by comparison between SNP patterns and factor analysis. Large scale analyses are required to ensure this tendency and to discover individual factors which may help to promote the health and QOL of the aged population.

KW - Low-resistance training

KW - Rehabilitation

KW - Single nucleotide polymorphism

KW - Vitmin D receptor

UR - http://www.scopus.com/inward/record.url?scp=61749097273&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=61749097273&partnerID=8YFLogxK

U2 - 10.3892/ijmm_00000104

DO - 10.3892/ijmm_00000104

M3 - Article

VL - 23

SP - 81

EP - 88

JO - International Journal of Molecular Medicine

JF - International Journal of Molecular Medicine

SN - 1107-3756

IS - 1

ER -