Effects of various drugs against Staphylococcus aureus: Role of zinc oxide, povidone-iodine, salts

H. Akiyama, Osamu Yamasaki, H. Kanzaki, J. Tada, J. Arata

Research output: Contribution to journalArticle

Abstract

The attachment of Staphylococcus aureus strain was weaker in plasma with 5% zinc oxide than in the control plasma without zinc oxide. The colonies on the immature biofilms completely disappeared in plasma with 5% zinc oxide and 0.2% hinokitiol. Ointment containing 5% zinc oxide was useful for atopic dermatitis lesions colonizing S. aureus at a density ≤ 1000 cfu/10cm2 (stamp method). But, we should use ointment containing 5% zinc oxide and 0.2% hinokitiol for atopic dermatitis lesions colonizing S. aureus at a density ≥ 1000 cfu/10cm2. 10% povidone-iodine solution was effective only for floating S. aureus cells which were not surrounded by fibrin bundles. 10% povidone- iodine solution was not effective for sessile cells and floating cells which were surrounded by fibrin bundles. We think that 10% povidone-iodine solution should be used in atopic dermatitis lesions colonizing S. aureus at a density ≥ 1000 cfu/10cm2 within a limited area for the shortest possible duration.

Original languageEnglish
Pages (from-to)111-116
Number of pages6
JournalSkin Research
Volume40
Issue numberSUPPL. 20
Publication statusPublished - 1998

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Zinc Oxide
Povidone-Iodine
Staphylococcus aureus
Salts
Atopic Dermatitis
Pharmaceutical Preparations
Ointments
Fibrin
Biofilms

Keywords

  • Atopic dermatitis
  • Povidone-iodine
  • Salt
  • Staphylococcus aureus
  • Zinc oxide

ASJC Scopus subject areas

  • Dermatology

Cite this

Akiyama, H., Yamasaki, O., Kanzaki, H., Tada, J., & Arata, J. (1998). Effects of various drugs against Staphylococcus aureus: Role of zinc oxide, povidone-iodine, salts. Skin Research, 40(SUPPL. 20), 111-116.

Effects of various drugs against Staphylococcus aureus : Role of zinc oxide, povidone-iodine, salts. / Akiyama, H.; Yamasaki, Osamu; Kanzaki, H.; Tada, J.; Arata, J.

In: Skin Research, Vol. 40, No. SUPPL. 20, 1998, p. 111-116.

Research output: Contribution to journalArticle

Akiyama, H, Yamasaki, O, Kanzaki, H, Tada, J & Arata, J 1998, 'Effects of various drugs against Staphylococcus aureus: Role of zinc oxide, povidone-iodine, salts', Skin Research, vol. 40, no. SUPPL. 20, pp. 111-116.
Akiyama, H. ; Yamasaki, Osamu ; Kanzaki, H. ; Tada, J. ; Arata, J. / Effects of various drugs against Staphylococcus aureus : Role of zinc oxide, povidone-iodine, salts. In: Skin Research. 1998 ; Vol. 40, No. SUPPL. 20. pp. 111-116.
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