Abstract
Background: In this study, whole krill oil (WKO) and phospholipid-type krill oil (PKO) with different lipid composition were prepared. The effects of KO intake on plasma cholesterol and glucose levels in Wistar rats fed a high-cholesterol diet (HCD) were investigated. Results: WKO contained 37.63% triglycerides, 48.37% phospholipids, 13.54% free fatty acids and 0.66% cholesterol, whereas the corresponding values for PKO were 0.59, 69.80, 28.53 and 1.09% respectively. Meanwhile, PKO contained much more polyunsaturated fatty acids (PUFA, 37.76%) than WKO (28.36%). After 4weeks of HCD consumption, plasma levels of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C) and glucose increased significantly, but that of high-density lipoprotein cholesterol (HDL-C) decreased significantly. The intake of PKO and WKO for 4weeks caused a significant reduction in body weight gain and plasma levels of TC and LDL-C in HCD-fed rats. Compared with WKO, PKO was more effective in decreasing plasma TC and LDL-C levels. Conclusion: PKO showed better overall cholesterol-lowering effects than WKO, which may be due to its higher n-3 PUFA levels.
| Original language | English |
|---|---|
| Pages (from-to) | 2669-2675 |
| Number of pages | 7 |
| Journal | Journal of the Science of Food and Agriculture |
| Volume | 93 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - Aug 30 2013 |
Keywords
- Cholesterol-lowering effect
- Glucose-lowering effect
- High-cholesterol-fed rat
- Krill oil
- Phospholipids
- n-3 polyunsaturated fatty acids
ASJC Scopus subject areas
- Biotechnology
- Food Science
- Agronomy and Crop Science
- Nutrition and Dietetics