Effects of increased ambient temperature on skin sympathetic nerve activity and core temperature in humans

Satoshi Iwase, Jian Cui, B. G. Wallin, Atsunori Kamiya, Tadaaki Mano

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

The strength of sympathetic vasoconstrictor nerve traffic to the skin has an important role in human thermoregulation since it controls heat loss from the skin by constricting or dilating cutaneous blood vessels. This study sought to clarify the time relationship between a reduction of the vasoconstrictor activity induced by elevating the ambient temperature (Ta), and subsequent change of core temperature (Tty). For this purpose, we recorded peroneal skin sympathetic nerve activity (SSNA), laser Doppler skin blood flow, skin and core (tympanic) temperatures in 11 subjects while increasing Ta from 15 to 30°C during ∼30 min. We observed a significant suppression of SSNA 7.7 min after Ta rise with marked interindividual variations. Tty displayed an increase with a peak after 8.2 min followed by a successive decrease, which became significant 14 min after the Ta rise. The rate of decrease of vasoconstrictor SSNA correlated both with the rate of decrease of Tty (P<0.01) and the magnitude of the Tty decrease (P<0.0005). A cross-correlogram between SSNA and Tty showed a peak at 7 min (r=0.52). We conclude that a Ta rise-induced reduction of skin vasoconstrictor nerve traffic leads to a core temperature decrease after 7-8 min.

Original languageEnglish
Pages (from-to)37-40
Number of pages4
JournalNeuroscience Letters
Volume327
Issue number1
DOIs
Publication statusPublished - Jul 12 2002
Externally publishedYes

Fingerprint

Skin Temperature
Skin
Temperature
Vasoconstrictor Agents
Body Temperature Regulation
Blood Vessels
Lasers
Hot Temperature

Keywords

  • Skin blood flow
  • Skin sympathetic nerve activity
  • Tympanic temperature
  • Vasoconstrictor

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Effects of increased ambient temperature on skin sympathetic nerve activity and core temperature in humans. / Iwase, Satoshi; Cui, Jian; Wallin, B. G.; Kamiya, Atsunori; Mano, Tadaaki.

In: Neuroscience Letters, Vol. 327, No. 1, 12.07.2002, p. 37-40.

Research output: Contribution to journalArticle

Iwase, Satoshi ; Cui, Jian ; Wallin, B. G. ; Kamiya, Atsunori ; Mano, Tadaaki. / Effects of increased ambient temperature on skin sympathetic nerve activity and core temperature in humans. In: Neuroscience Letters. 2002 ; Vol. 327, No. 1. pp. 37-40.
@article{c2869c5823814d16bb088288e47f17ba,
title = "Effects of increased ambient temperature on skin sympathetic nerve activity and core temperature in humans",
abstract = "The strength of sympathetic vasoconstrictor nerve traffic to the skin has an important role in human thermoregulation since it controls heat loss from the skin by constricting or dilating cutaneous blood vessels. This study sought to clarify the time relationship between a reduction of the vasoconstrictor activity induced by elevating the ambient temperature (Ta), and subsequent change of core temperature (Tty). For this purpose, we recorded peroneal skin sympathetic nerve activity (SSNA), laser Doppler skin blood flow, skin and core (tympanic) temperatures in 11 subjects while increasing Ta from 15 to 30°C during ∼30 min. We observed a significant suppression of SSNA 7.7 min after Ta rise with marked interindividual variations. Tty displayed an increase with a peak after 8.2 min followed by a successive decrease, which became significant 14 min after the Ta rise. The rate of decrease of vasoconstrictor SSNA correlated both with the rate of decrease of Tty (P<0.01) and the magnitude of the Tty decrease (P<0.0005). A cross-correlogram between SSNA and Tty showed a peak at 7 min (r=0.52). We conclude that a Ta rise-induced reduction of skin vasoconstrictor nerve traffic leads to a core temperature decrease after 7-8 min.",
keywords = "Skin blood flow, Skin sympathetic nerve activity, Tympanic temperature, Vasoconstrictor",
author = "Satoshi Iwase and Jian Cui and Wallin, {B. G.} and Atsunori Kamiya and Tadaaki Mano",
year = "2002",
month = "7",
day = "12",
doi = "10.1016/S0304-3940(02)00374-9",
language = "English",
volume = "327",
pages = "37--40",
journal = "Neuroscience Letters",
issn = "0304-3940",
publisher = "Elsevier Ireland Ltd",
number = "1",

}

TY - JOUR

T1 - Effects of increased ambient temperature on skin sympathetic nerve activity and core temperature in humans

AU - Iwase, Satoshi

AU - Cui, Jian

AU - Wallin, B. G.

AU - Kamiya, Atsunori

AU - Mano, Tadaaki

PY - 2002/7/12

Y1 - 2002/7/12

N2 - The strength of sympathetic vasoconstrictor nerve traffic to the skin has an important role in human thermoregulation since it controls heat loss from the skin by constricting or dilating cutaneous blood vessels. This study sought to clarify the time relationship between a reduction of the vasoconstrictor activity induced by elevating the ambient temperature (Ta), and subsequent change of core temperature (Tty). For this purpose, we recorded peroneal skin sympathetic nerve activity (SSNA), laser Doppler skin blood flow, skin and core (tympanic) temperatures in 11 subjects while increasing Ta from 15 to 30°C during ∼30 min. We observed a significant suppression of SSNA 7.7 min after Ta rise with marked interindividual variations. Tty displayed an increase with a peak after 8.2 min followed by a successive decrease, which became significant 14 min after the Ta rise. The rate of decrease of vasoconstrictor SSNA correlated both with the rate of decrease of Tty (P<0.01) and the magnitude of the Tty decrease (P<0.0005). A cross-correlogram between SSNA and Tty showed a peak at 7 min (r=0.52). We conclude that a Ta rise-induced reduction of skin vasoconstrictor nerve traffic leads to a core temperature decrease after 7-8 min.

AB - The strength of sympathetic vasoconstrictor nerve traffic to the skin has an important role in human thermoregulation since it controls heat loss from the skin by constricting or dilating cutaneous blood vessels. This study sought to clarify the time relationship between a reduction of the vasoconstrictor activity induced by elevating the ambient temperature (Ta), and subsequent change of core temperature (Tty). For this purpose, we recorded peroneal skin sympathetic nerve activity (SSNA), laser Doppler skin blood flow, skin and core (tympanic) temperatures in 11 subjects while increasing Ta from 15 to 30°C during ∼30 min. We observed a significant suppression of SSNA 7.7 min after Ta rise with marked interindividual variations. Tty displayed an increase with a peak after 8.2 min followed by a successive decrease, which became significant 14 min after the Ta rise. The rate of decrease of vasoconstrictor SSNA correlated both with the rate of decrease of Tty (P<0.01) and the magnitude of the Tty decrease (P<0.0005). A cross-correlogram between SSNA and Tty showed a peak at 7 min (r=0.52). We conclude that a Ta rise-induced reduction of skin vasoconstrictor nerve traffic leads to a core temperature decrease after 7-8 min.

KW - Skin blood flow

KW - Skin sympathetic nerve activity

KW - Tympanic temperature

KW - Vasoconstrictor

UR - http://www.scopus.com/inward/record.url?scp=0037067505&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037067505&partnerID=8YFLogxK

U2 - 10.1016/S0304-3940(02)00374-9

DO - 10.1016/S0304-3940(02)00374-9

M3 - Article

C2 - 12098495

AN - SCOPUS:0037067505

VL - 327

SP - 37

EP - 40

JO - Neuroscience Letters

JF - Neuroscience Letters

SN - 0304-3940

IS - 1

ER -