Effects of fujibitol, a remedy for nasal symptoms of immediate and delayed type allergic reactions

Masanori Kakimoto, Naoyuki Takasugi, Tohru Fuwa, Hiroshi Saito, Yukio Sugimoto, Chiaki Kamei

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The effects of Fujibitol, a remedy for the nasal symptoms of immediate and delayed type allergic reactions were studied. Fujibitol inhibited active systemic anaphylaxis in mice, heterologous passive cutaneous anaphylaxis (PCA) in rats, Masugi's nephritis in rats and delayed type hypersensitivity induced by picryl chloride in mice, but did not affect homologous PCA or immune complex-induced glomerulonephritis in rats. These results suggested that Fujibitol is effective for treatment of allergy-induced inflammation since IgG and type IV allergic reactions were inhibited.

Original languageEnglish
Pages (from-to)353-356
Number of pages4
JournalMethods and Findings in Experimental and Clinical Pharmacology
Volume21
Issue number5
DOIs
Publication statusPublished - 1999

Fingerprint

Nose
Hypersensitivity
Passive Cutaneous Anaphylaxis
Picryl Chloride
Nephritis
Delayed Hypersensitivity
Anaphylaxis
Glomerulonephritis
Antigen-Antibody Complex
Immunoglobulin G
Inflammation
Fujibitol

Keywords

  • Antiallergic
  • Antiinflammatory
  • Fujibitol
  • Preparation of crude drugs

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Effects of fujibitol, a remedy for nasal symptoms of immediate and delayed type allergic reactions. / Kakimoto, Masanori; Takasugi, Naoyuki; Fuwa, Tohru; Saito, Hiroshi; Sugimoto, Yukio; Kamei, Chiaki.

In: Methods and Findings in Experimental and Clinical Pharmacology, Vol. 21, No. 5, 1999, p. 353-356.

Research output: Contribution to journalArticle

Kakimoto, Masanori ; Takasugi, Naoyuki ; Fuwa, Tohru ; Saito, Hiroshi ; Sugimoto, Yukio ; Kamei, Chiaki. / Effects of fujibitol, a remedy for nasal symptoms of immediate and delayed type allergic reactions. In: Methods and Findings in Experimental and Clinical Pharmacology. 1999 ; Vol. 21, No. 5. pp. 353-356.
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