Effects of Endoluminal Stent-Grafts on Acute Aortic Dissection in Dogs

Keiji Yunoki, Hatuzo Uchida, Shunji Sano, Nobuyoshi Shimizu

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Acute aortic dissection is a life-threatening condition, and may be treated with aggressive hypotensive drug therapy, but emergency surgery is often necessary. We evaluated the effectiveness of stent-grafts for the treatment of acute aortic dissection. Aortic dissection was surgically created in the descending thoracic aorta in 20 adult mongrel dogs. A stent-graft was inserted in the entry position. The tested animals were divided into 4 groups based on re-entry type and blood pressure alteration rate (AR) after acute aortic dissection. After insertion of the stent, the following results were observed: a) AR improved; b) proximal descending aorta and superior mesenteric arterial flows increased; c) cardiac function improved; and d) the dissecting aortic diameter decreased in the presence of pressure gradient group. From these results, insertion of a stent-graft to treat acute aortic dissection was judged to be effective.

Original languageEnglish
Pages (from-to)89-95
Number of pages7
JournalActa Medica Okayama
Volume52
Issue number2
Publication statusPublished - Apr 1998

Fingerprint

Dissection
Stents
Grafts
Dogs
Transplants
Thoracic Aorta
Drug therapy
Reentry
Blood pressure
Pressure gradient
Surgery
Animals
Emergencies
Blood Pressure
Pressure
Drug Therapy

Keywords

  • Acute aortic dissection
  • Blanton's method
  • Endoluminal graft
  • Stent-graft

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Yunoki, K., Uchida, H., Sano, S., & Shimizu, N. (1998). Effects of Endoluminal Stent-Grafts on Acute Aortic Dissection in Dogs. Acta Medica Okayama, 52(2), 89-95.

Effects of Endoluminal Stent-Grafts on Acute Aortic Dissection in Dogs. / Yunoki, Keiji; Uchida, Hatuzo; Sano, Shunji; Shimizu, Nobuyoshi.

In: Acta Medica Okayama, Vol. 52, No. 2, 04.1998, p. 89-95.

Research output: Contribution to journalArticle

Yunoki, K, Uchida, H, Sano, S & Shimizu, N 1998, 'Effects of Endoluminal Stent-Grafts on Acute Aortic Dissection in Dogs', Acta Medica Okayama, vol. 52, no. 2, pp. 89-95.
Yunoki K, Uchida H, Sano S, Shimizu N. Effects of Endoluminal Stent-Grafts on Acute Aortic Dissection in Dogs. Acta Medica Okayama. 1998 Apr;52(2):89-95.
Yunoki, Keiji ; Uchida, Hatuzo ; Sano, Shunji ; Shimizu, Nobuyoshi. / Effects of Endoluminal Stent-Grafts on Acute Aortic Dissection in Dogs. In: Acta Medica Okayama. 1998 ; Vol. 52, No. 2. pp. 89-95.
@article{f6671c6e3c0f47bca54975c99ce1f006,
title = "Effects of Endoluminal Stent-Grafts on Acute Aortic Dissection in Dogs",
abstract = "Acute aortic dissection is a life-threatening condition, and may be treated with aggressive hypotensive drug therapy, but emergency surgery is often necessary. We evaluated the effectiveness of stent-grafts for the treatment of acute aortic dissection. Aortic dissection was surgically created in the descending thoracic aorta in 20 adult mongrel dogs. A stent-graft was inserted in the entry position. The tested animals were divided into 4 groups based on re-entry type and blood pressure alteration rate (AR) after acute aortic dissection. After insertion of the stent, the following results were observed: a) AR improved; b) proximal descending aorta and superior mesenteric arterial flows increased; c) cardiac function improved; and d) the dissecting aortic diameter decreased in the presence of pressure gradient group. From these results, insertion of a stent-graft to treat acute aortic dissection was judged to be effective.",
keywords = "Acute aortic dissection, Blanton's method, Endoluminal graft, Stent-graft",
author = "Keiji Yunoki and Hatuzo Uchida and Shunji Sano and Nobuyoshi Shimizu",
year = "1998",
month = "4",
language = "English",
volume = "52",
pages = "89--95",
journal = "Acta Medica Okayama",
issn = "0386-300X",
publisher = "Okayama University",
number = "2",

}

TY - JOUR

T1 - Effects of Endoluminal Stent-Grafts on Acute Aortic Dissection in Dogs

AU - Yunoki, Keiji

AU - Uchida, Hatuzo

AU - Sano, Shunji

AU - Shimizu, Nobuyoshi

PY - 1998/4

Y1 - 1998/4

N2 - Acute aortic dissection is a life-threatening condition, and may be treated with aggressive hypotensive drug therapy, but emergency surgery is often necessary. We evaluated the effectiveness of stent-grafts for the treatment of acute aortic dissection. Aortic dissection was surgically created in the descending thoracic aorta in 20 adult mongrel dogs. A stent-graft was inserted in the entry position. The tested animals were divided into 4 groups based on re-entry type and blood pressure alteration rate (AR) after acute aortic dissection. After insertion of the stent, the following results were observed: a) AR improved; b) proximal descending aorta and superior mesenteric arterial flows increased; c) cardiac function improved; and d) the dissecting aortic diameter decreased in the presence of pressure gradient group. From these results, insertion of a stent-graft to treat acute aortic dissection was judged to be effective.

AB - Acute aortic dissection is a life-threatening condition, and may be treated with aggressive hypotensive drug therapy, but emergency surgery is often necessary. We evaluated the effectiveness of stent-grafts for the treatment of acute aortic dissection. Aortic dissection was surgically created in the descending thoracic aorta in 20 adult mongrel dogs. A stent-graft was inserted in the entry position. The tested animals were divided into 4 groups based on re-entry type and blood pressure alteration rate (AR) after acute aortic dissection. After insertion of the stent, the following results were observed: a) AR improved; b) proximal descending aorta and superior mesenteric arterial flows increased; c) cardiac function improved; and d) the dissecting aortic diameter decreased in the presence of pressure gradient group. From these results, insertion of a stent-graft to treat acute aortic dissection was judged to be effective.

KW - Acute aortic dissection

KW - Blanton's method

KW - Endoluminal graft

KW - Stent-graft

UR - http://www.scopus.com/inward/record.url?scp=0032044618&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032044618&partnerID=8YFLogxK

M3 - Article

C2 - 9588224

AN - SCOPUS:0032044618

VL - 52

SP - 89

EP - 95

JO - Acta Medica Okayama

JF - Acta Medica Okayama

SN - 0386-300X

IS - 2

ER -