Abstract
Objective: The effects of perilla seed oil (n-3 fatty acids) on bronchial asthma were compared with the effects of corn oil (n-6 fatty acids) in relation to the pulmonary function and the generation of leukotriene B4 (LTB4) and C4 (LTC4) by leucocytes. Methods and Subjects: 14 asthmatic subjects were divided randomly into two groups: one group (7 subjects) consumed perilla seed oil-rich supplementation and the other group (7 subjects) consumed corn oil-rich supplementation for 4 weeks. Generation of LTs by leucocytes and respiratory function were compared between the two groups. Results: The generation of LTB4 and LTC4 by leucocytes tended to increase in subjects (N=7) with corn oil-rich supplementation, and decrease in subjects (N=7) with perilla seed oil-rich supplementation. Significant differences between the two groups were observed in the generation of LTB4 at 2 weeks (p1.0 (p25 (p1.0 (p
| Original language | English |
|---|---|
| Pages (from-to) | 107-111 |
| Number of pages | 5 |
| Journal | Internal Medicine |
| Volume | 39 |
| Issue number | 2 |
| Publication status | Published - 2000 |
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Keywords
- α-linolenic acid
- Leukotriene B4
- Leukotriene C4
- Perilla seed oil
- Respiratory function
ASJC Scopus subject areas
- Internal Medicine
Cite this
Effects of dietary supplementation with N-3 fatty acids compared with N- 6 fatty acids on bronchial asthma. / Okamoto, M.; Mitsunobu, Fumihiro; Ashida, Kozo; Mifune, T.; Hosaki, Y.; Tsugeno, H.; Harada, S.; Tanizaki, Y.
In: Internal Medicine, Vol. 39, No. 2, 2000, p. 107-111.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effects of dietary supplementation with N-3 fatty acids compared with N- 6 fatty acids on bronchial asthma
AU - Okamoto, M.
AU - Mitsunobu, Fumihiro
AU - Ashida, Kozo
AU - Mifune, T.
AU - Hosaki, Y.
AU - Tsugeno, H.
AU - Harada, S.
AU - Tanizaki, Y.
PY - 2000
Y1 - 2000
N2 - Objective: The effects of perilla seed oil (n-3 fatty acids) on bronchial asthma were compared with the effects of corn oil (n-6 fatty acids) in relation to the pulmonary function and the generation of leukotriene B4 (LTB4) and C4 (LTC4) by leucocytes. Methods and Subjects: 14 asthmatic subjects were divided randomly into two groups: one group (7 subjects) consumed perilla seed oil-rich supplementation and the other group (7 subjects) consumed corn oil-rich supplementation for 4 weeks. Generation of LTs by leucocytes and respiratory function were compared between the two groups. Results: The generation of LTB4 and LTC4 by leucocytes tended to increase in subjects (N=7) with corn oil-rich supplementation, and decrease in subjects (N=7) with perilla seed oil-rich supplementation. Significant differences between the two groups were observed in the generation of LTB4 at 2 weeks (p1.0 (p25 (p1.0 (p
AB - Objective: The effects of perilla seed oil (n-3 fatty acids) on bronchial asthma were compared with the effects of corn oil (n-6 fatty acids) in relation to the pulmonary function and the generation of leukotriene B4 (LTB4) and C4 (LTC4) by leucocytes. Methods and Subjects: 14 asthmatic subjects were divided randomly into two groups: one group (7 subjects) consumed perilla seed oil-rich supplementation and the other group (7 subjects) consumed corn oil-rich supplementation for 4 weeks. Generation of LTs by leucocytes and respiratory function were compared between the two groups. Results: The generation of LTB4 and LTC4 by leucocytes tended to increase in subjects (N=7) with corn oil-rich supplementation, and decrease in subjects (N=7) with perilla seed oil-rich supplementation. Significant differences between the two groups were observed in the generation of LTB4 at 2 weeks (p1.0 (p25 (p1.0 (p
KW - α-linolenic acid
KW - Leukotriene B4
KW - Leukotriene C4
KW - Perilla seed oil
KW - Respiratory function
UR - http://www.scopus.com/inward/record.url?scp=0034069617&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0034069617&partnerID=8YFLogxK
M3 - Article
C2 - 10732825
AN - SCOPUS:0034069617
VL - 39
SP - 107
EP - 111
JO - Internal Medicine
JF - Internal Medicine
SN - 0918-2918
IS - 2
ER -