Effects of diaphragm plication for phrenic nerve paralysis on respiratory mechanics and diaphragm function

S. Takeda, K. Nakahara, Y. Fujii, S. Miyoshi, T. Mizuta, M. Minami, H. Matsuda

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The purpose of this study is to examine the effects of unilateral diaphragm plication for phrenic nerve paralysis on the respiratory mechanics and diaphragm function. Study 1: We performed thoracotomy (BASELINE), left phrenicotomy (INJURY) and left diaphragm plication (PLICATION) in ten dogs. After chest was closed in each condition, measured were the tidal volume (TV), respiratory rate (f), esophageal and gastric pressure swing (delta Pes, delta Pga), dynamic compliance (Cdyn) the ratio of gastric to esophageal pressure swing (delta Pga/delta Pes) and the work of breathing per liter (WOB/L) under stable spontaneous breathing. Study 2: In eight other left-phrenicotomized dogs, Pdi and fractional shortening of the costal diaphragm during contralateral electrophrenic stimulation were measured before and after plication. After plication TV, delta Pga/delta Pes, Cdyn, Pdi and fractional shortening during stimulation increased significantly, whereas Pes and WOB/L decreased significantly compared with INJURY condition. In conclusion unilateral diaphragm plication after paralysis improves the intact hemidiaphragm contractility and diaphragmatic contribution to breathing.

Original languageEnglish
Pages (from-to)1367-1370
Number of pages4
JournalNippon Geka Gakkai zasshi
Volume92
Issue number9
Publication statusPublished - Sep 1991
Externally publishedYes

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Respiratory Mechanics
Phrenic Nerve
Diaphragm
Paralysis
Work of Breathing
Tidal Volume
Stomach
Respiration
Dogs
Pressure
Thoracotomy
Respiratory Rate
Compliance
Thorax

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Takeda, S., Nakahara, K., Fujii, Y., Miyoshi, S., Mizuta, T., Minami, M., & Matsuda, H. (1991). Effects of diaphragm plication for phrenic nerve paralysis on respiratory mechanics and diaphragm function. Nippon Geka Gakkai zasshi, 92(9), 1367-1370.

Effects of diaphragm plication for phrenic nerve paralysis on respiratory mechanics and diaphragm function. / Takeda, S.; Nakahara, K.; Fujii, Y.; Miyoshi, S.; Mizuta, T.; Minami, M.; Matsuda, H.

In: Nippon Geka Gakkai zasshi, Vol. 92, No. 9, 09.1991, p. 1367-1370.

Research output: Contribution to journalArticle

Takeda, S, Nakahara, K, Fujii, Y, Miyoshi, S, Mizuta, T, Minami, M & Matsuda, H 1991, 'Effects of diaphragm plication for phrenic nerve paralysis on respiratory mechanics and diaphragm function', Nippon Geka Gakkai zasshi, vol. 92, no. 9, pp. 1367-1370.
Takeda S, Nakahara K, Fujii Y, Miyoshi S, Mizuta T, Minami M et al. Effects of diaphragm plication for phrenic nerve paralysis on respiratory mechanics and diaphragm function. Nippon Geka Gakkai zasshi. 1991 Sep;92(9):1367-1370.
Takeda, S. ; Nakahara, K. ; Fujii, Y. ; Miyoshi, S. ; Mizuta, T. ; Minami, M. ; Matsuda, H. / Effects of diaphragm plication for phrenic nerve paralysis on respiratory mechanics and diaphragm function. In: Nippon Geka Gakkai zasshi. 1991 ; Vol. 92, No. 9. pp. 1367-1370.
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