Effects of cuminaldehyde on melanoma cells

Teruhiko Nitoda, Maria D. Fan, Isao Kubo

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Cuminaldehyde (4-isopropylbenzaldehyde) suppressed melanin formation in cultured murine B16-F10 melanoma cells in a dose-dependent decrease up to 0.25 mm without affecting cell growth. Approximately 30% suppression in melanin production resulted when the cells were cultured with 0.25 mm of cuminaldehyde. This activity was not noticeable with cultured human A375 melanoma cells.

Original languageEnglish
Pages (from-to)809-813
Number of pages5
JournalPhytotherapy Research
Volume22
Issue number6
DOIs
Publication statusPublished - Jun 2008
Externally publishedYes

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Keywords

  • B16-F10 melanoma cell
  • Cuminaldehyde
  • Melanin formation

ASJC Scopus subject areas

  • Drug Discovery
  • Organic Chemistry
  • Pharmacology

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