Effectiveness of pressure support ventilation for mechanical ventilatory support in patients with status asthmaticus

H. Tokioka, Shinya Saito, T. Takahashi, M. Kinjo, S. Saeki, F. Kosaka, M. Hirakawa

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

We compared the effects of pressure support ventilation (PSV) with those of assist control ventrilation (ACV) on breathing patterns and blood gas exchange in six patients with status asthmaticus. Both PSV and ACV delivered adequate minute ventilation (PSV: 7.5 ± 1.4 l/min/m2, ACV: 7.3 ± 1.3 l/min/m2) to correct respiratory acidosis (pH = 7.33 ± 0.12 during both PSV and ACV) and prevent hypoxia. Peak airway pressure during PSV was significantly lower with the same tidal volume than that during ACV (PSV: 30 ± 10 cmH2O (2.9 ± 1.0 kPa), ACV: 50 ± 13 cmH2O (4.9 ± 1.3 kPa)). The lower airway pressure during PSV was due to persistant inspiratory muscle activity. The oxygen cost of breathing estimated by oxygen consumption was equivalent in both modes. We conclude that PSV is effective in supplying tidal volumes adequate to improve hypercarbia at markedly lower airway pressures than ACV.

Original languageEnglish
Pages (from-to)5-9
Number of pages5
JournalActa Anaesthesiologica Scandinavica
Volume36
Issue number1
Publication statusPublished - 1992

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Status Asthmaticus
Artificial Respiration
Ventilation
Pressure
Tidal Volume
Respiration
Respiratory Acidosis
Hypercapnia
Oxygen Consumption

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Cite this

Effectiveness of pressure support ventilation for mechanical ventilatory support in patients with status asthmaticus. / Tokioka, H.; Saito, Shinya; Takahashi, T.; Kinjo, M.; Saeki, S.; Kosaka, F.; Hirakawa, M.

In: Acta Anaesthesiologica Scandinavica, Vol. 36, No. 1, 1992, p. 5-9.

Research output: Contribution to journalArticle

Tokioka, H. ; Saito, Shinya ; Takahashi, T. ; Kinjo, M. ; Saeki, S. ; Kosaka, F. ; Hirakawa, M. / Effectiveness of pressure support ventilation for mechanical ventilatory support in patients with status asthmaticus. In: Acta Anaesthesiologica Scandinavica. 1992 ; Vol. 36, No. 1. pp. 5-9.
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