Effect of thymectomy for myasthenia gravis

T. Nakamura, R. Kono, T. Yamane, Toshihiko Matsuo, H. Ootsuki, A. Andou

Research output: Contribution to journalArticle

Abstract

We reviewed 4 cases of myasthenia gravis with ocular involvement treated by extended thymectomy. None of the cases had thymoma or responded to systemic corticosteroid. The ages ranged from 54 to 69 years, average 62 years. Myasthenia gravis had been present for 4 to 288 months. Cases were followed up for up to 57 months after surgery. Complete and partial remission of systemic symptoms resulted in 2 cases each. All the 4 cases showed cure of blepharoptosis and improvement in ocular deviations. Diplopia persisted in 2 cases including one with long-standing history. The findings show the usefulness of early thymectomy for myasthenia gravis with ocular involvement which fails to respond to medications including systemic corticosteroid.

Original languageEnglish
Pages (from-to)795-798
Number of pages4
JournalJapanese Journal of Clinical Ophthalmology
Volume54
Issue number5
Publication statusPublished - 2000

Fingerprint

Thymectomy
Myasthenia Gravis
Adrenal Cortex Hormones
Blepharoptosis
Diplopia
Thymoma
History

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Nakamura, T., Kono, R., Yamane, T., Matsuo, T., Ootsuki, H., & Andou, A. (2000). Effect of thymectomy for myasthenia gravis. Japanese Journal of Clinical Ophthalmology, 54(5), 795-798.

Effect of thymectomy for myasthenia gravis. / Nakamura, T.; Kono, R.; Yamane, T.; Matsuo, Toshihiko; Ootsuki, H.; Andou, A.

In: Japanese Journal of Clinical Ophthalmology, Vol. 54, No. 5, 2000, p. 795-798.

Research output: Contribution to journalArticle

Nakamura, T, Kono, R, Yamane, T, Matsuo, T, Ootsuki, H & Andou, A 2000, 'Effect of thymectomy for myasthenia gravis', Japanese Journal of Clinical Ophthalmology, vol. 54, no. 5, pp. 795-798.
Nakamura T, Kono R, Yamane T, Matsuo T, Ootsuki H, Andou A. Effect of thymectomy for myasthenia gravis. Japanese Journal of Clinical Ophthalmology. 2000;54(5):795-798.
Nakamura, T. ; Kono, R. ; Yamane, T. ; Matsuo, Toshihiko ; Ootsuki, H. ; Andou, A. / Effect of thymectomy for myasthenia gravis. In: Japanese Journal of Clinical Ophthalmology. 2000 ; Vol. 54, No. 5. pp. 795-798.
@article{c2cea1c49d4e4019a88f6757051fea45,
title = "Effect of thymectomy for myasthenia gravis",
abstract = "We reviewed 4 cases of myasthenia gravis with ocular involvement treated by extended thymectomy. None of the cases had thymoma or responded to systemic corticosteroid. The ages ranged from 54 to 69 years, average 62 years. Myasthenia gravis had been present for 4 to 288 months. Cases were followed up for up to 57 months after surgery. Complete and partial remission of systemic symptoms resulted in 2 cases each. All the 4 cases showed cure of blepharoptosis and improvement in ocular deviations. Diplopia persisted in 2 cases including one with long-standing history. The findings show the usefulness of early thymectomy for myasthenia gravis with ocular involvement which fails to respond to medications including systemic corticosteroid.",
author = "T. Nakamura and R. Kono and T. Yamane and Toshihiko Matsuo and H. Ootsuki and A. Andou",
year = "2000",
language = "English",
volume = "54",
pages = "795--798",
journal = "Japanese Journal of Clinical Ophthalmology",
issn = "0370-5579",
publisher = "Igaku-Shoin Ltd",
number = "5",

}

TY - JOUR

T1 - Effect of thymectomy for myasthenia gravis

AU - Nakamura, T.

AU - Kono, R.

AU - Yamane, T.

AU - Matsuo, Toshihiko

AU - Ootsuki, H.

AU - Andou, A.

PY - 2000

Y1 - 2000

N2 - We reviewed 4 cases of myasthenia gravis with ocular involvement treated by extended thymectomy. None of the cases had thymoma or responded to systemic corticosteroid. The ages ranged from 54 to 69 years, average 62 years. Myasthenia gravis had been present for 4 to 288 months. Cases were followed up for up to 57 months after surgery. Complete and partial remission of systemic symptoms resulted in 2 cases each. All the 4 cases showed cure of blepharoptosis and improvement in ocular deviations. Diplopia persisted in 2 cases including one with long-standing history. The findings show the usefulness of early thymectomy for myasthenia gravis with ocular involvement which fails to respond to medications including systemic corticosteroid.

AB - We reviewed 4 cases of myasthenia gravis with ocular involvement treated by extended thymectomy. None of the cases had thymoma or responded to systemic corticosteroid. The ages ranged from 54 to 69 years, average 62 years. Myasthenia gravis had been present for 4 to 288 months. Cases were followed up for up to 57 months after surgery. Complete and partial remission of systemic symptoms resulted in 2 cases each. All the 4 cases showed cure of blepharoptosis and improvement in ocular deviations. Diplopia persisted in 2 cases including one with long-standing history. The findings show the usefulness of early thymectomy for myasthenia gravis with ocular involvement which fails to respond to medications including systemic corticosteroid.

UR - http://www.scopus.com/inward/record.url?scp=0034086920&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034086920&partnerID=8YFLogxK

M3 - Article

VL - 54

SP - 795

EP - 798

JO - Japanese Journal of Clinical Ophthalmology

JF - Japanese Journal of Clinical Ophthalmology

SN - 0370-5579

IS - 5

ER -