Effect of Intracoronary Thrombectomy on 30-Day Mortality in Patients With Acute Myocardial Infarction

Daisaku Nakatani, Hiroshi Sato, Yasuhiko Sakata, Hiroya Mizuno, Masahiko Shimizu, Shinichiro Suna, Shinsuke Nanto, Atsushi Hirayama, Hiroshi Itoh, Kenshi Fujii, Masatsugu Hori

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Insertion of intracoronary thrombectomy (ICT) devices, as a precedent to percutaneous coronary intervention (PCI), theoretically could have a beneficial effect on the outcome in patients with acute myocardial infarction. To examine whether ICT was associated with a lower 30-day mortality rate in patients with acute myocardial infarction, we studied 3,913 patients who underwent PCI within 24 hours after onset. A total of 990 patients (25.3%) were treated with ICT before PCI. The 30-day mortality rate was lower in the patients receiving ICT than in those without (3.7% vs 6.2%, p = 0.004), but this beneficial effect disappeared after adjustment for baseline characteristics (hazard ratio [HR] 0.658, p = 0.166). We also divided the patients into tertiles according to the Thrombolysis In Myocardial Infarction (TIMI) risk score. After adjustment for baseline characteristics, ICT was associated with a lower 30-day mortality rate in patients from the highest TIMI risk score tertile (HR 0.407, p = 0.029), but not in patients from the lower 2 tertiles. ICT was also an independent predictor of a lower 30-day mortality risk in patients aged ≥70 years (HR 0.239, p = 0.007), patients with diabetes mellitus (HR 0.275, p = 0.039), and those with stent implantation (HR 0.437, p = 0.034). In conclusion, in selected patients with high TIMI risk scores, an age ≥70 years, diabetes mellitus, or stenting, ICT is associated with a lower 30-day mortality rate.

Original languageEnglish
Pages (from-to)1212-1217
Number of pages6
JournalAmerican Journal of Cardiology
Volume100
Issue number8
DOIs
Publication statusPublished - Oct 15 2007
Externally publishedYes

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Thrombectomy
Myocardial Infarction
Mortality
Percutaneous Coronary Intervention
Diabetes Mellitus
Stents

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Effect of Intracoronary Thrombectomy on 30-Day Mortality in Patients With Acute Myocardial Infarction. / Nakatani, Daisaku; Sato, Hiroshi; Sakata, Yasuhiko; Mizuno, Hiroya; Shimizu, Masahiko; Suna, Shinichiro; Nanto, Shinsuke; Hirayama, Atsushi; Itoh, Hiroshi; Fujii, Kenshi; Hori, Masatsugu.

In: American Journal of Cardiology, Vol. 100, No. 8, 15.10.2007, p. 1212-1217.

Research output: Contribution to journalArticle

Nakatani, D, Sato, H, Sakata, Y, Mizuno, H, Shimizu, M, Suna, S, Nanto, S, Hirayama, A, Itoh, H, Fujii, K & Hori, M 2007, 'Effect of Intracoronary Thrombectomy on 30-Day Mortality in Patients With Acute Myocardial Infarction', American Journal of Cardiology, vol. 100, no. 8, pp. 1212-1217. https://doi.org/10.1016/j.amjcard.2007.05.040
Nakatani, Daisaku ; Sato, Hiroshi ; Sakata, Yasuhiko ; Mizuno, Hiroya ; Shimizu, Masahiko ; Suna, Shinichiro ; Nanto, Shinsuke ; Hirayama, Atsushi ; Itoh, Hiroshi ; Fujii, Kenshi ; Hori, Masatsugu. / Effect of Intracoronary Thrombectomy on 30-Day Mortality in Patients With Acute Myocardial Infarction. In: American Journal of Cardiology. 2007 ; Vol. 100, No. 8. pp. 1212-1217.
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AU - Suna, Shinichiro

AU - Nanto, Shinsuke

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AU - Fujii, Kenshi

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