Effect of glutaraldehyde on properties of membranes prepared from fish scale collagen

Zhefeng Xu, Toshiyuki Ikoma, Tomohiko Yoshioka, Motohiro Tagaya, Satoshi Motozuka, Rena Matsumoto, Toshimasa Uemura, Junzo Tanaka

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

Collagen fibril membranes (CFMs) with a high mechanical property were fabricated with a lateral face evaporation method, in which type I atelocollagen extracted from tilapia scales was used. The density and thickness of the CFM obtained were 0.51 ± 0.04 mg/cm 3 and 50 ± 5 μm. The collagen fibrils in the CFM had a similar periodic stripped pattern of 67 nm with native collagen fibrils. The CFM was crosslinked in gaseous glutaraldehyde for different duration in order to increase the mechanical property. The crosslinking degrees of the CFMs analyzed by free amino groups gradually increased to 70.3 % against the exposure duration until 6 hours, and reached a plateau. The denaturation temperatures of the CFMs with the crosslinking degrees at 20.4 % to 43% were linearly increased from 49°C to 75°C. The tensile strength of the CFMs was slightly improved until the crosslinking degree at 33.3 % and then the tensile strength rapidly increased to be 68 MPa. It was suggested that a percolation phenomenon took place in the CFMs by crosslinking of collagen fibrils with polymerized GA molecules.

Original languageEnglish
Title of host publicationMaterials Research Society Symposium Proceedings
Pages189-194
Number of pages6
Volume1418
DOIs
Publication statusPublished - 2012
Externally publishedYes
Event2011 MRS Fall Meeting - Boston, MA, United States
Duration: Nov 28 2011Dec 2 2011

Other

Other2011 MRS Fall Meeting
CountryUnited States
CityBoston, MA
Period11/28/1112/2/11

Fingerprint

fishes
Glutaral
collagens
Collagen
Fish
membranes
Membranes
crosslinking
Crosslinking
tensile strength
Tensile strength
mechanical properties
Mechanical properties
Denaturation
biopolymer denaturation
plateaus
Evaporation
evaporation
Molecules

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanical Engineering
  • Mechanics of Materials

Cite this

Xu, Z., Ikoma, T., Yoshioka, T., Tagaya, M., Motozuka, S., Matsumoto, R., ... Tanaka, J. (2012). Effect of glutaraldehyde on properties of membranes prepared from fish scale collagen. In Materials Research Society Symposium Proceedings (Vol. 1418, pp. 189-194) https://doi.org/10.1557/opl.2012.396

Effect of glutaraldehyde on properties of membranes prepared from fish scale collagen. / Xu, Zhefeng; Ikoma, Toshiyuki; Yoshioka, Tomohiko; Tagaya, Motohiro; Motozuka, Satoshi; Matsumoto, Rena; Uemura, Toshimasa; Tanaka, Junzo.

Materials Research Society Symposium Proceedings. Vol. 1418 2012. p. 189-194.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Xu, Z, Ikoma, T, Yoshioka, T, Tagaya, M, Motozuka, S, Matsumoto, R, Uemura, T & Tanaka, J 2012, Effect of glutaraldehyde on properties of membranes prepared from fish scale collagen. in Materials Research Society Symposium Proceedings. vol. 1418, pp. 189-194, 2011 MRS Fall Meeting, Boston, MA, United States, 11/28/11. https://doi.org/10.1557/opl.2012.396
Xu Z, Ikoma T, Yoshioka T, Tagaya M, Motozuka S, Matsumoto R et al. Effect of glutaraldehyde on properties of membranes prepared from fish scale collagen. In Materials Research Society Symposium Proceedings. Vol. 1418. 2012. p. 189-194 https://doi.org/10.1557/opl.2012.396
Xu, Zhefeng ; Ikoma, Toshiyuki ; Yoshioka, Tomohiko ; Tagaya, Motohiro ; Motozuka, Satoshi ; Matsumoto, Rena ; Uemura, Toshimasa ; Tanaka, Junzo. / Effect of glutaraldehyde on properties of membranes prepared from fish scale collagen. Materials Research Society Symposium Proceedings. Vol. 1418 2012. pp. 189-194
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