Effect of eccentric contractions of elbow flexor on bone formation and resorption markers

Y. Tsuchiya, K. Sakuraba, E. Ochi

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AIM: This study aimed to investigate the effects of eccentric contractions (ECs) of the biceps brachii muscle on bone metabolism markers.

METHODS: Eight untrained subjects (20.0±0.5 years) performed 5 sets of 6 maximal ECs of the elbow flexors with a 2-min rest interval between each set. Blood samples were collected at 6 time points: before (Pre) ECs, immediately after (Post) ECs, and two hours (2 hours), 1 (day 1), 3 (days 3), and 5 days (days 5) after ECs. We measured the levels of the bone formation marker osteocalcin (OC) and the resorption marker tartrate-resistant acid phosphatase 5b (TRACP-5b). In addition, we measured the isometric tetanic torque and the levels of myoglobin (Mb), creatine kinase (CK), blood lactate, and insulin-like growth factor-1 (IGF-1).

RESULTS: The results showed 1) CK and Mb levels increased significantly by days 3 and 5 (P

CONCLUSION: We conclude that a single bout of ECs of the biceps has a negative effect on bone metabolism in the acute phase.

Original languageEnglish
Pages (from-to)651-657
Number of pages7
JournalThe Journal of sports medicine and physical fitness
Issue number5
Publication statusPublished - Oct 1 2014
Externally publishedYes


ASJC Scopus subject areas

  • Medicine(all)

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