Effect of addition of glucose on micellar electrokinetic capillary chromatography with sodium dodecyl sulphate

Takashi Kaneta, Shunitz Tanaka, Mitsuhiko Taga, Hitoshi Yoshida

Research output: Contribution to journalArticle

35 Citations (Scopus)


Glucose was investigated as a possible additive for the improvement of resolution in micellar electrokinetic capillary chromatography. Addition of glucose to the micellar solution facilitated the complete separation of a mixture of nine nucleosides by both extending the elution range and changing the selectivity. Extension of the elution range can be attributed to an increase in the electrophoretic mobility of the micelle. It is also apparent that glucose selectively reduces the distribution coefficients for solutes containing a hydrophilic functional group. This effect was valuable in the separation of some solutes with hydrophilic functional groups and large capacity factors.

Original languageEnglish
Pages (from-to)369-374
Number of pages6
JournalJournal of Chromatography A
Issue number1-2
Publication statusPublished - Sep 18 1992
Externally publishedYes


ASJC Scopus subject areas

  • Analytical Chemistry
  • Clinical Biochemistry
  • Molecular Medicine

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