EcR-A expression in the brain and ovary of the honeybee (Apis mellifera L.)

Hideaki Takeuchi, Rajib Kumar Paul, Emiko Matsuzaka, Takeo Kubo

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

We previously demonstrated that six genes involved in ecdysteroid signaling are expressed preferentially in Kenyon-cell subtypes in the mushroom bodies of the honeybee (Apis mellifera L.). To further examine the possible involvement of ecdysteroid signaling in honeybee brain function, we isolated a cDNA for the A isoform of the ecdysone receptor gene homolog AmEcR-A and analyzed its expression in the brain. In situ hybridization revealed that AmEcR-A is expressed selectively in the small-type Kenyon cells of the mushroom bodies in the worker and queen brain, like AmE74 and AmHR38, suggesting a possible association of these gene products. Analysis of AmEcR-A expression in queen and worker abdomens demonstrated that AmEcR-A is strongly expressed in nurse cells of the queen ovary, suggesting that ecdysteroid and ecdysteroid signaling have roles in oogenesis. Our present results further support the possible involvement of ecdysteroid signaling in brain function, as well as in regulating queen reproductive physiology in the adult honeybee.

Original languageEnglish
Pages (from-to)596-603
Number of pages8
JournalZoological Science
Volume24
Issue number6
DOIs
Publication statusPublished - Jun 2007
Externally publishedYes

Fingerprint

ecdysteroids
Apis mellifera
honey bees
brain
queen insects
mushroom bodies
queen cells
genes
animal reproduction
oogenesis
nurses
abdomen
in situ hybridization
cells

Keywords

  • Ecdysone receptor
  • Ecdysteroid
  • Gene expression
  • Honeybee
  • Mushroom body
  • Ovary

ASJC Scopus subject areas

  • Animal Science and Zoology

Cite this

EcR-A expression in the brain and ovary of the honeybee (Apis mellifera L.). / Takeuchi, Hideaki; Paul, Rajib Kumar; Matsuzaka, Emiko; Kubo, Takeo.

In: Zoological Science, Vol. 24, No. 6, 06.2007, p. 596-603.

Research output: Contribution to journalArticle

Takeuchi, Hideaki ; Paul, Rajib Kumar ; Matsuzaka, Emiko ; Kubo, Takeo. / EcR-A expression in the brain and ovary of the honeybee (Apis mellifera L.). In: Zoological Science. 2007 ; Vol. 24, No. 6. pp. 596-603.
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