Eccrine poromatosis associated with polychemotherapy

Kazuyasu Fujii, Seiko Aochi, Chinatsu Takeshima, Masaki Ohtsuka, Toshihisa Hamada, Kenji Asagoe, Yumi Aoyama, Shin Morizane, Keiji Iwatsuki

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Abstract

Eccrine poroma frequently occurs as a solitary tumour, and only a few reports have described the occurrence of multiple lesions. Multiple eccrine poromas, or eccrine poromatosis, may occur in patients who have undergone radiotherapy and/or polychemotherapy. We report here four cases of multiple eccrine poromas in patients who were either undergoing, or had undergone, intensive chemotherapy (from 6 months to 16 years prior to onset). Three patients had non-Hodgkin's lymphoma and one had malignant fibrous histiocytosis. The number of lesions varied from 3 to > 20 in each patient, and all the lesions occurred on non-irradiated skin. The histopathological features were consistent with those of eccrine poroma, Pinkus type. In addition to radiation therapy, intensive chemotherapy may play a role in the pathogenesis of multiple eccrine poromas even many years after treatment.

Original languageEnglish
Pages (from-to)687-690
Number of pages4
JournalActa Dermato-Venereologica
Volume92
Issue number6
DOIs
Publication statusPublished - 2012

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Keywords

  • Chemotherapy
  • Eccrine poroma
  • Multiple
  • Poromatosis

ASJC Scopus subject areas

  • Dermatology

Cite this

Fujii, K., Aochi, S., Takeshima, C., Ohtsuka, M., Hamada, T., Asagoe, K., Aoyama, Y., Morizane, S., & Iwatsuki, K. (2012). Eccrine poromatosis associated with polychemotherapy. Acta Dermato-Venereologica, 92(6), 687-690. https://doi.org/10.2340/00015555-1279