TY - JOUR
T1 - Early Afterdepolarization Abolished by Potassium Channel Opener in a Patient with Idiopathic Long QT Syndrome
AU - SATO, TETSUYA
AU - HATA, YOSHIKI
AU - YAMAMOTO, MIKA
AU - MORITA, HIROSHI
AU - MIZUO, KOZO
AU - YAMANARI, HIROSHI
AU - SAITO, DAIJI
AU - OHE, TOHRU
PY - 1995/4
Y1 - 1995/4
N2 - Abolished Early Afterdepolarization by Nicorandil. We describe a 17‐year‐old boy with idiopathic long QT syndrome and repeated syncopal episodes. Early afterdepolarization (EAD) in the monophasic action potential (MAP) was demonstrated in the posterior septum of the left ventricle. Injection of the potassium channel opener nicorandil decreased KAD and shortened MAP duration. The syncopal episodes due to ventricular fibrillation disappeared after administration of the potassium channel opener.
AB - Abolished Early Afterdepolarization by Nicorandil. We describe a 17‐year‐old boy with idiopathic long QT syndrome and repeated syncopal episodes. Early afterdepolarization (EAD) in the monophasic action potential (MAP) was demonstrated in the posterior septum of the left ventricle. Injection of the potassium channel opener nicorandil decreased KAD and shortened MAP duration. The syncopal episodes due to ventricular fibrillation disappeared after administration of the potassium channel opener.
KW - early afterdepolarization
KW - idiopathic long QT syndrome
KW - monophasic action potential
KW - potassium channel opener
KW - ventricular fibrillation
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U2 - 10.1111/j.1540-8167.1995.tb00400.x
DO - 10.1111/j.1540-8167.1995.tb00400.x
M3 - Article
C2 - 7647953
AN - SCOPUS:0029021031
VL - 6
SP - 279
EP - 282
JO - Journal of Cardiovascular Electrophysiology
JF - Journal of Cardiovascular Electrophysiology
SN - 1045-3873
IS - 4
ER -