Abstract
Abolished Early Afterdepolarization by Nicorandil. We describe a 17-year- old boy with idiopathic long QT syndrome and repeated syncopal episodes. Early afterdepolarization (EAD) in the monophasic action potential (MAP) was demonstrated in the posterior septum of the left ventricle. Injection of the potassium channel opener nicorandil decreased EAD and shortened MAP duration. The syncopal episodes due to ventricular fibrillation disappeared after administration of the potassium channel opener.
| Original language | English |
|---|---|
| Pages (from-to) | 279-282 |
| Number of pages | 4 |
| Journal | Journal of Cardiovascular Electrophysiology |
| Volume | 6 |
| Issue number | 4 |
| Publication status | Published - 1995 |
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Keywords
- early afterdepolarization
- idiopathic long QT syndrome
- monophasic action potential
- potassium channel opener
- ventricular fibrillation
ASJC Scopus subject areas
- Physiology
- Cardiology and Cardiovascular Medicine
Cite this
Early afterdepolarization abolished by potassium channel opener in a patient with idiopathic long QT syndrome. / Sato, T.; Hata, Y.; Yamamoto, M.; Morita, Hiroshi; Mizuo, K.; Yamanari, H.; Saito, D.; Ohe, T.
In: Journal of Cardiovascular Electrophysiology, Vol. 6, No. 4, 1995, p. 279-282.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Early afterdepolarization abolished by potassium channel opener in a patient with idiopathic long QT syndrome
AU - Sato, T.
AU - Hata, Y.
AU - Yamamoto, M.
AU - Morita, Hiroshi
AU - Mizuo, K.
AU - Yamanari, H.
AU - Saito, D.
AU - Ohe, T.
PY - 1995
Y1 - 1995
N2 - Abolished Early Afterdepolarization by Nicorandil. We describe a 17-year- old boy with idiopathic long QT syndrome and repeated syncopal episodes. Early afterdepolarization (EAD) in the monophasic action potential (MAP) was demonstrated in the posterior septum of the left ventricle. Injection of the potassium channel opener nicorandil decreased EAD and shortened MAP duration. The syncopal episodes due to ventricular fibrillation disappeared after administration of the potassium channel opener.
AB - Abolished Early Afterdepolarization by Nicorandil. We describe a 17-year- old boy with idiopathic long QT syndrome and repeated syncopal episodes. Early afterdepolarization (EAD) in the monophasic action potential (MAP) was demonstrated in the posterior septum of the left ventricle. Injection of the potassium channel opener nicorandil decreased EAD and shortened MAP duration. The syncopal episodes due to ventricular fibrillation disappeared after administration of the potassium channel opener.
KW - early afterdepolarization
KW - idiopathic long QT syndrome
KW - monophasic action potential
KW - potassium channel opener
KW - ventricular fibrillation
UR - http://www.scopus.com/inward/record.url?scp=0029021031&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0029021031&partnerID=8YFLogxK
M3 - Article
C2 - 7647953
AN - SCOPUS:0029021031
VL - 6
SP - 279
EP - 282
JO - Journal of Cardiovascular Electrophysiology
JF - Journal of Cardiovascular Electrophysiology
SN - 1045-3873
IS - 4
ER -