Dynamics of a highly branched lipid bilayer: A molecular dynamics study

Wataru Shinoda, Masuhiro Mikami, Teruhiko Baba, Masakatsu Hato

Research output: Contribution to journalArticlepeer-review

40 Citations (Scopus)

Abstract

A comparison of branch-chained diphytanoylphosphatidylcholine (DPhPC) and straight-chained dipalmitoylphosphatidylcholine (DPPC) for their dynamics in the bilayers is made using 10 ns molecular dynamics simulations in the microcanonical ensemble. It is demonstrated that DPhPC molecules, compared with DPPC, indeed have slower wobbling, rotational, and translational motions by a factor of 2-3, whereas slightly faster headgroup rotation. The revision of the lipid dynamics due to chain branching is similar to that observed by the addition of cholesterol.

Original languageEnglish
Pages (from-to)35-40
Number of pages6
JournalChemical Physics Letters
Volume390
Issue number1-3
DOIs
Publication statusPublished - May 21 2004
Externally publishedYes

ASJC Scopus subject areas

  • Physics and Astronomy(all)
  • Physical and Theoretical Chemistry

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