Dye-coupling of melanocytes with endothelial cells and pericytes in the cochlea of gerbils

Shunji Takeuchi, Motonori Ando

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

Intercellular connections via gap junctions in the stria vascularis, which constitutes the lateral wall of the cochlear duct, were investigated by the Lucifer yellow microinjection method with the aid of a confocal laser microscope. The dye injected into an intermediate cell (melanocyte) diffused into capillary endothelial cells and pericytes as well as other intermediate cells, basal cells, and fibrocytes in the spiral ligament; whereas the dye injected into a marginal cell (epithelial cell) was confined to the injected cell. The observation of dye-coupling between intermediate cells and endothelial cells and pericytes makes likely the possibility that these cells work together to play a role in the specific function of the stria vascularis (i.e., production of the positive endocochlear potential and the endolymph) and adds endothelial cells and pericytes to the current 'two-cell model' of the stria vascularis.

Original languageEnglish
Pages (from-to)271-275
Number of pages5
JournalCell and Tissue Research
Volume293
Issue number2
DOIs
Publication statusPublished - 1998
Externally publishedYes

Fingerprint

Pericytes
Gerbillinae
Melanocytes
Cochlea
Endothelial cells
Coloring Agents
Endothelial Cells
Stria Vascularis
Ligaments
Ducts
Microscopes
Cells
Lasers
Spiral Ligament of Cochlea
Cochlear Duct
Endolymph
Gap Junctions
Microinjections
Epithelial Cells
Observation

Keywords

  • Gap junction
  • Gerbil
  • Intermediate cell
  • Lucifer yellow
  • Microinjection
  • Stria vascularis

ASJC Scopus subject areas

  • Anatomy
  • Clinical Biochemistry
  • Cell Biology

Cite this

Dye-coupling of melanocytes with endothelial cells and pericytes in the cochlea of gerbils. / Takeuchi, Shunji; Ando, Motonori.

In: Cell and Tissue Research, Vol. 293, No. 2, 1998, p. 271-275.

Research output: Contribution to journalArticle

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