Drastic enhancement of the enantioselectivity of lipase-catalysed esterification in organic solvents by the addition of metal ions

Takashi Okamoto, Shinichi Ueji

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

By the addition of metal ion-containing water, a marked enhancement of the enantioselectivity for the lipase-catalysed esterification of 2-(4-substituted-phenoxy)propionic acids in Pr(i)2O was observed, the mechanism of which will be discussed briefly on the basis of the initial rate obtained for each enantiomer of the substrate.

Original languageEnglish
Pages (from-to)939-940
Number of pages2
JournalChemical Communications
Issue number10
Publication statusPublished - May 21 1999
Externally publishedYes

Fingerprint

Propionic acid
Enantiomers
Enantioselectivity
Propionates
Lipases
Esterification
Lipase
Organic solvents
Metal ions
Water
Substrates

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

@article{65c3736955714272be28771dcae8b6a0,
title = "Drastic enhancement of the enantioselectivity of lipase-catalysed esterification in organic solvents by the addition of metal ions",
abstract = "By the addition of metal ion-containing water, a marked enhancement of the enantioselectivity for the lipase-catalysed esterification of 2-(4-substituted-phenoxy)propionic acids in Pr(i)2O was observed, the mechanism of which will be discussed briefly on the basis of the initial rate obtained for each enantiomer of the substrate.",
author = "Takashi Okamoto and Shinichi Ueji",
year = "1999",
month = "5",
day = "21",
language = "English",
pages = "939--940",
journal = "Chemical Communications",
issn = "1359-7345",
publisher = "Royal Society of Chemistry",
number = "10",

}

TY - JOUR

T1 - Drastic enhancement of the enantioselectivity of lipase-catalysed esterification in organic solvents by the addition of metal ions

AU - Okamoto, Takashi

AU - Ueji, Shinichi

PY - 1999/5/21

Y1 - 1999/5/21

N2 - By the addition of metal ion-containing water, a marked enhancement of the enantioselectivity for the lipase-catalysed esterification of 2-(4-substituted-phenoxy)propionic acids in Pr(i)2O was observed, the mechanism of which will be discussed briefly on the basis of the initial rate obtained for each enantiomer of the substrate.

AB - By the addition of metal ion-containing water, a marked enhancement of the enantioselectivity for the lipase-catalysed esterification of 2-(4-substituted-phenoxy)propionic acids in Pr(i)2O was observed, the mechanism of which will be discussed briefly on the basis of the initial rate obtained for each enantiomer of the substrate.

UR - http://www.scopus.com/inward/record.url?scp=0033591415&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033591415&partnerID=8YFLogxK

M3 - Article

SP - 939

EP - 940

JO - Chemical Communications

JF - Chemical Communications

SN - 1359-7345

IS - 10

ER -