Drastic enhancement of the enantioselectivity of lipase-catalysed esterification in organic solvents by the addition of metal ions

Takashi Okamoto, Shinichi Ueji

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

By the addition of metal ion-containing water, a marked enhancement of the enantioselectivity for the lipase-catalysed esterification of 2-(4-substituted-phenoxy)propionic acids in Pr(i)2O was observed, the mechanism of which will be discussed briefly on the basis of the initial rate obtained for each enantiomer of the substrate.

Original languageEnglish
Pages (from-to)939-940
Number of pages2
JournalChemical Communications
Issue number10
Publication statusPublished - May 21 1999
Externally publishedYes

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ASJC Scopus subject areas

  • Chemistry(all)

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