Double high-dose chemotherapy supported by autologous transplantation of peripheral blood stem cells for treatment of an elderly patient with small-cell lung cancer

Hiromichi Yamane, Akihiro Bessho, Katsuyuki Kiura, Masahiro Tabata, Yoshio Katayama, Kinya Motoda, Tadashi Tsuchida, Naoyuki Nogami, Akio Hiraki, Hiroshi Ueoka, Mine Harada

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We report a 62-year-old male with extensive disease small-cell lung cancer (SCLC) who was successfully treated with double high-dose chemotherapy supported by autologous peripheral blood stem cell transplantation (auto-PBSCT). This patient achieved a partial response with 3 cycles of induction chemotherapy. After the peripheral blood stem cell mobilization, two cycles of high-dose ICE regimen (ifosfamide 3,000 mg/m2 at days 1 to 5, carboplatin 400 mg/m2 at days 1,3, 5, and etoposide 500 mg/m2 at days 1,3,5) could be given with further regression of the tumor and acceptable toxicities. This successful case suggests the feasibility of double high-dose ICE with auto-PBSCT in elderly patients with SCLC.

Original languageEnglish
Pages (from-to)892-895
Number of pages4
JournalInternal Medicine
Volume38
Issue number11
DOIs
Publication statusPublished - Nov 1999

Keywords

  • Autologous peripheral blood stem cell transplantation (auto-PBSCT)
  • Double transplantation

ASJC Scopus subject areas

  • Internal Medicine

Fingerprint Dive into the research topics of 'Double high-dose chemotherapy supported by autologous transplantation of peripheral blood stem cells for treatment of an elderly patient with small-cell lung cancer'. Together they form a unique fingerprint.

  • Cite this