Double high-dose chemotherapy supported by autologous transplantation of peripheral blood stem cells for treatment of an elderly patient with small-cell lung cancer

Hiromichi Yamane; Akihiro Bessho; Katsuyuki Kiura; Masahiro Tabata; Yoshio Katayama; Kinya Motoda; Tadashi Tsuchida; Naoyuki Nogami; Akio Hiraki; Hiroshi Ueoka; Mine Harada

doi:10.2169/internalmedicine.38.892

Double high-dose chemotherapy supported by autologous transplantation of peripheral blood stem cells for treatment of an elderly patient with small-cell lung cancer

Hiromichi Yamane, Akihiro Bessho, Katsuyuki Kiura, Masahiro Tabata, Yoshio Katayama, Kinya Motoda, Tadashi Tsuchida, Naoyuki Nogami, Akio Hiraki, Hiroshi Ueoka, Mine Harada

University Hospital

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

We report a 62-year-old male with extensive disease small-cell lung cancer (SCLC) who was successfully treated with double high-dose chemotherapy supported by autologous peripheral blood stem cell transplantation (auto-PBSCT). This patient achieved a partial response with 3 cycles of induction chemotherapy. After the peripheral blood stem cell mobilization, two cycles of high-dose ICE regimen (ifosfamide 3,000 mg/m² at days 1 to 5, carboplatin 400 mg/m² at days 1,3, 5, and etoposide 500 mg/m² at days 1,3,5) could be given with further regression of the tumor and acceptable toxicities. This successful case suggests the feasibility of double high-dose ICE with auto-PBSCT in elderly patients with SCLC.

Original language	English
Pages (from-to)	892-895
Number of pages	4
Journal	Internal Medicine
Volume	38
Issue number	11
DOIs	https://doi.org/10.2169/internalmedicine.38.892
Publication status	Published - Nov 1999

Keywords

Autologous peripheral blood stem cell transplantation (auto-PBSCT)
Double transplantation

ASJC Scopus subject areas

Internal Medicine

UN SDGs

This output contributes to the following Sustainable Development Goal(s)

Access to Document

10.2169/internalmedicine.38.892

Fingerprint Dive into the research topics of 'Double high-dose chemotherapy supported by autologous transplantation of peripheral blood stem cells for treatment of an elderly patient with small-cell lung cancer'. Together they form a unique fingerprint.

Cite this

Yamane, H., Bessho, A., Kiura, K., Tabata, M., Katayama, Y., Motoda, K., Tsuchida, T., Nogami, N., Hiraki, A., Ueoka, H., & Harada, M. (1999). Double high-dose chemotherapy supported by autologous transplantation of peripheral blood stem cells for treatment of an elderly patient with small-cell lung cancer. Internal Medicine, 38(11), 892-895. https://doi.org/10.2169/internalmedicine.38.892

Double high-dose chemotherapy supported by autologous transplantation of peripheral blood stem cells for treatment of an elderly patient with small-cell lung cancer. / Yamane, Hiromichi; Bessho, Akihiro; Kiura, Katsuyuki ; Tabata, Masahiro; Katayama, Yoshio; Motoda, Kinya; Tsuchida, Tadashi; Nogami, Naoyuki; Hiraki, Akio; Ueoka, Hiroshi; Harada, Mine.

In: Internal Medicine, Vol. 38, No. 11, 11.1999, p. 892-895.

Research output: Contribution to journal › Article › peer-review

Yamane, H, Bessho, A, Kiura, K , Tabata, M, Katayama, Y, Motoda, K, Tsuchida, T, Nogami, N, Hiraki, A, Ueoka, H & Harada, M 1999, 'Double high-dose chemotherapy supported by autologous transplantation of peripheral blood stem cells for treatment of an elderly patient with small-cell lung cancer', Internal Medicine, vol. 38, no. 11, pp. 892-895. https://doi.org/10.2169/internalmedicine.38.892

Yamane, Hiromichi ; Bessho, Akihiro ; Kiura, Katsuyuki ; Tabata, Masahiro ; Katayama, Yoshio ; Motoda, Kinya ; Tsuchida, Tadashi ; Nogami, Naoyuki ; Hiraki, Akio ; Ueoka, Hiroshi ; Harada, Mine. / Double high-dose chemotherapy supported by autologous transplantation of peripheral blood stem cells for treatment of an elderly patient with small-cell lung cancer. In: Internal Medicine. 1999 ; Vol. 38, No. 11. pp. 892-895.

@article{bfd9bb6e626c4f84bdce1a2092e696a4,

title = "Double high-dose chemotherapy supported by autologous transplantation of peripheral blood stem cells for treatment of an elderly patient with small-cell lung cancer",

abstract = "We report a 62-year-old male with extensive disease small-cell lung cancer (SCLC) who was successfully treated with double high-dose chemotherapy supported by autologous peripheral blood stem cell transplantation (auto-PBSCT). This patient achieved a partial response with 3 cycles of induction chemotherapy. After the peripheral blood stem cell mobilization, two cycles of high-dose ICE regimen (ifosfamide 3,000 mg/m2 at days 1 to 5, carboplatin 400 mg/m2 at days 1,3, 5, and etoposide 500 mg/m2 at days 1,3,5) could be given with further regression of the tumor and acceptable toxicities. This successful case suggests the feasibility of double high-dose ICE with auto-PBSCT in elderly patients with SCLC.",

keywords = "Autologous peripheral blood stem cell transplantation (auto-PBSCT), Double transplantation",

author = "Hiromichi Yamane and Akihiro Bessho and Katsuyuki Kiura and Masahiro Tabata and Yoshio Katayama and Kinya Motoda and Tadashi Tsuchida and Naoyuki Nogami and Akio Hiraki and Hiroshi Ueoka and Mine Harada",

year = "1999",

month = nov,

doi = "10.2169/internalmedicine.38.892",

language = "English",

volume = "38",

pages = "892--895",

journal = "Internal Medicine",

issn = "0918-2918",

publisher = "Japanese Society of Internal Medicine",

number = "11",

}

TY - JOUR

T1 - Double high-dose chemotherapy supported by autologous transplantation of peripheral blood stem cells for treatment of an elderly patient with small-cell lung cancer

AU - Yamane, Hiromichi

AU - Bessho, Akihiro

AU - Kiura, Katsuyuki

AU - Tabata, Masahiro

AU - Katayama, Yoshio

AU - Motoda, Kinya

AU - Tsuchida, Tadashi

AU - Nogami, Naoyuki

AU - Hiraki, Akio

AU - Ueoka, Hiroshi

AU - Harada, Mine

PY - 1999/11

Y1 - 1999/11

N2 - We report a 62-year-old male with extensive disease small-cell lung cancer (SCLC) who was successfully treated with double high-dose chemotherapy supported by autologous peripheral blood stem cell transplantation (auto-PBSCT). This patient achieved a partial response with 3 cycles of induction chemotherapy. After the peripheral blood stem cell mobilization, two cycles of high-dose ICE regimen (ifosfamide 3,000 mg/m2 at days 1 to 5, carboplatin 400 mg/m2 at days 1,3, 5, and etoposide 500 mg/m2 at days 1,3,5) could be given with further regression of the tumor and acceptable toxicities. This successful case suggests the feasibility of double high-dose ICE with auto-PBSCT in elderly patients with SCLC.

AB - We report a 62-year-old male with extensive disease small-cell lung cancer (SCLC) who was successfully treated with double high-dose chemotherapy supported by autologous peripheral blood stem cell transplantation (auto-PBSCT). This patient achieved a partial response with 3 cycles of induction chemotherapy. After the peripheral blood stem cell mobilization, two cycles of high-dose ICE regimen (ifosfamide 3,000 mg/m2 at days 1 to 5, carboplatin 400 mg/m2 at days 1,3, 5, and etoposide 500 mg/m2 at days 1,3,5) could be given with further regression of the tumor and acceptable toxicities. This successful case suggests the feasibility of double high-dose ICE with auto-PBSCT in elderly patients with SCLC.

KW - Autologous peripheral blood stem cell transplantation (auto-PBSCT)

KW - Double transplantation

UR - http://www.scopus.com/inward/record.url?scp=0032726889&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032726889&partnerID=8YFLogxK

U2 - 10.2169/internalmedicine.38.892

DO - 10.2169/internalmedicine.38.892

M3 - Article

C2 - 10563752

AN - SCOPUS:0032726889

VL - 38

SP - 892

EP - 895

JO - Internal Medicine

JF - Internal Medicine

SN - 0918-2918

IS - 11

ER -

Double high-dose chemotherapy supported by autologous transplantation of peripheral blood stem cells for treatment of an elderly patient with small-cell lung cancer

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Cite this