Does diffusion-weighted magnetic resonance imaging enable detection of early ischemic change following transient cerebral ischemia?

Hidero Kawahara, Yoshimasa Takeda, Akio Tanaka, Osamu Nagano, Hiroshi Katayama, Masahisa Hirakawa, Yoshio Hiraki

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

To examine the usefulness of diffusion-weighted imaging for detecting neuronal damage following ischemia, dynamic changes in diffusion-, T1- and T2-weighted images of rats subjected to 10 min of 4-vessel occlusion and of humans who had suffered 10-20 min of cardiac arrest were observed. In rats, no remarkable alteration was observed on day 1. On day 3, however, diffusion-weighted images showed high signal intensity in the hippocampal area, in which the apparent diffusion coefficient was significantly lower than that of the control (760±28 x 10-6 mm2/s in control vs. 480±29 x 10-6 mm2/s on day 3, P

Original languageEnglish
Pages (from-to)73-81
Number of pages9
JournalJournal of the Neurological Sciences
Volume181
Issue number1-2
DOIs
Publication statusPublished - Dec 1 2000

Fingerprint

Diffusion Magnetic Resonance Imaging
Transient Ischemic Attack
Heart Arrest
Ischemia

Keywords

  • Basal ganglia
  • Brain death
  • Cardiopulmonary resuscitation
  • Cerebral anoxia
  • Cerebral cortex
  • Cerebral ischemia
  • Magnetic resonance imaging
  • Persistent vegetative state

ASJC Scopus subject areas

  • Ageing
  • Clinical Neurology
  • Surgery
  • Developmental Neuroscience
  • Neurology
  • Neuroscience(all)

Cite this

Does diffusion-weighted magnetic resonance imaging enable detection of early ischemic change following transient cerebral ischemia? / Kawahara, Hidero; Takeda, Yoshimasa; Tanaka, Akio; Nagano, Osamu; Katayama, Hiroshi; Hirakawa, Masahisa; Hiraki, Yoshio.

In: Journal of the Neurological Sciences, Vol. 181, No. 1-2, 01.12.2000, p. 73-81.

Research output: Contribution to journalArticle

Kawahara, Hidero ; Takeda, Yoshimasa ; Tanaka, Akio ; Nagano, Osamu ; Katayama, Hiroshi ; Hirakawa, Masahisa ; Hiraki, Yoshio. / Does diffusion-weighted magnetic resonance imaging enable detection of early ischemic change following transient cerebral ischemia?. In: Journal of the Neurological Sciences. 2000 ; Vol. 181, No. 1-2. pp. 73-81.
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