Diverse roles of single membrane organelles: Factors establishing the acid lumenal pH1

Masamitsu Futai, Toshihiko Oka, Yoshinori Moriyama, Yoh Wada

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

Eukaryotic cells have developed an array of endomembrane systems that have differentiated to carry out various functions. They are involved in the pathways of endocytosis and exocytosis, and have an acidic lumenal pH ranging from 4.5 to 6.5. This review describes recent studies on the animal cell organelles and how they relate to the well studied systems of yeast. We focus mainly on (i) the primary proton pump (vacuolar type H+-ATPase) and other factors that establish acidic pH, and (ii) functions of the organelles as related to lumenal acidity.

Original languageEnglish
Pages (from-to)259-267
Number of pages9
JournalJournal of Biochemistry
Volume124
Issue number2
Publication statusPublished - Aug 1998
Externally publishedYes

Fingerprint

Organelles
Vacuolar Proton-Translocating ATPases
Membranes
Proton Pumps
Acids
Exocytosis
Eukaryotic Cells
Endocytosis
Acidity
Yeast
Animals
Yeasts
Cells

Keywords

  • Acidification
  • Endocytosis
  • Exocytosis
  • H-ATPase
  • Membrane traffic

ASJC Scopus subject areas

  • Biochemistry

Cite this

Futai, M., Oka, T., Moriyama, Y., & Wada, Y. (1998). Diverse roles of single membrane organelles: Factors establishing the acid lumenal pH1. Journal of Biochemistry, 124(2), 259-267.

Diverse roles of single membrane organelles : Factors establishing the acid lumenal pH1. / Futai, Masamitsu; Oka, Toshihiko; Moriyama, Yoshinori; Wada, Yoh.

In: Journal of Biochemistry, Vol. 124, No. 2, 08.1998, p. 259-267.

Research output: Contribution to journalArticle

Futai, M, Oka, T, Moriyama, Y & Wada, Y 1998, 'Diverse roles of single membrane organelles: Factors establishing the acid lumenal pH1', Journal of Biochemistry, vol. 124, no. 2, pp. 259-267.
Futai, Masamitsu ; Oka, Toshihiko ; Moriyama, Yoshinori ; Wada, Yoh. / Diverse roles of single membrane organelles : Factors establishing the acid lumenal pH1. In: Journal of Biochemistry. 1998 ; Vol. 124, No. 2. pp. 259-267.
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