Divalent cations elevate cytosolic calcium of chick osteocytes

Hiroshi Kamioka, Koji Sumitani, Kahori Tagami, Yoshiki Miki, Kunihiro Terai, Yoshiyuki Hakeda, Masayoshi Kumegawa, Terushige Kawata

Research output: Contribution to journalArticle

14 Citations (Scopus)


Though it is proposed that osteocytes have several functions in bone metabolism, only limited definite information including results of calcium regulation has been forthcoming. We demonstrate here for the first time that the concentration of divalent cations, such as calcium, nickel and cadmium, directly regulates the cytosolic calcium concentration in osteocytes.

Original languageEnglish
Pages (from-to)519-524
Number of pages6
JournalBiochemical and Biophysical Research Communications
Issue number2
Publication statusPublished - Oct 31 1994
Externally publishedYes


ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

Cite this

Kamioka, H., Sumitani, K., Tagami, K., Miki, Y., Terai, K., Hakeda, Y., Kumegawa, M., & Kawata, T. (1994). Divalent cations elevate cytosolic calcium of chick osteocytes. Biochemical and Biophysical Research Communications, 204(2), 519-524. https://doi.org/10.1006/bbrc.1994.2490