Dissemination of carbapenemase-producing Enterobacteriaceae harbouring bla NDM or bla IMI in local market foods of Yangon, Myanmar

Yo Sugawara, Hideharu Hagiya, Yukihiro Akeda, Mya Mya Aye, Hpoo Pwint Myo Win, Noriko Sakamoto, Rathina Kumar Shanmugakani, Dan Takeuchi, Isao Nishi, Akiko Ueda, Moh Moh Htun, Kazunori Tomono, Shigeyuki Hamada

Research output: Contribution to journalArticle

Abstract

The spread of carbapenemase-producing Enterobacteriaceae (CPE) poses a serious threat to clinical practice and public health. These bacteria are present both in clinical settings and non-clinical environments. The presence of CPE in food stuffs has been reported, but sporadically so. Here, we screened for CPE in meat, seafood, and vegetable samples from local markets of Yangon, Myanmar. We obtained 27 CPE isolates from 93 food samples and identified 13 as Escherichia coli, six as Klebsiella pneumoniae, seven as Enterobacter cloacae complex, and one as Serratia marcescens. All except the E. cloacae complex harboured the carbapenemase genes blaNDM-1 or blaNDM-5, while all Enterobacter isolates carried the carbapenemase gene blaIMI-1. The blaIMI-1 gene was located in putative mobile elements EcloIMEX-2, -3, or -8. Using multi-locus sequence typing, E. coli, K. pneumoniae, and E. cloacae complex isolates were classified into 10, six, and five different sequence types, respectively. Our results demonstrate that diverse organisms with various carbapenemase genes are widespread in the market foods in Yangon, highlighting the need for promoting proper food hygiene and effective measures to prevent further dissemination.

Original languageEnglish
Article number14455
JournalScientific reports
Volume9
Issue number1
DOIs
Publication statusPublished - Dec 1 2019
Externally publishedYes

Fingerprint

Myanmar
Enterobacteriaceae
Food
Enterobacter cloacae
Klebsiella pneumoniae
Genes
Escherichia coli
Public Health Practice
Seafood
Enterobacter
Serratia marcescens
carbapenemase
Hygiene
Vegetables
Meat
Bacteria

ASJC Scopus subject areas

  • General

Cite this

Dissemination of carbapenemase-producing Enterobacteriaceae harbouring bla NDM or bla IMI in local market foods of Yangon, Myanmar. / Sugawara, Yo; Hagiya, Hideharu; Akeda, Yukihiro; Aye, Mya Mya; Myo Win, Hpoo Pwint; Sakamoto, Noriko; Shanmugakani, Rathina Kumar; Takeuchi, Dan; Nishi, Isao; Ueda, Akiko; Htun, Moh Moh; Tomono, Kazunori; Hamada, Shigeyuki.

In: Scientific reports, Vol. 9, No. 1, 14455, 01.12.2019.

Research output: Contribution to journalArticle

Sugawara, Y, Hagiya, H, Akeda, Y, Aye, MM, Myo Win, HP, Sakamoto, N, Shanmugakani, RK, Takeuchi, D, Nishi, I, Ueda, A, Htun, MM, Tomono, K & Hamada, S 2019, 'Dissemination of carbapenemase-producing Enterobacteriaceae harbouring bla NDM or bla IMI in local market foods of Yangon, Myanmar', Scientific reports, vol. 9, no. 1, 14455. https://doi.org/10.1038/s41598-019-51002-5
Sugawara, Yo ; Hagiya, Hideharu ; Akeda, Yukihiro ; Aye, Mya Mya ; Myo Win, Hpoo Pwint ; Sakamoto, Noriko ; Shanmugakani, Rathina Kumar ; Takeuchi, Dan ; Nishi, Isao ; Ueda, Akiko ; Htun, Moh Moh ; Tomono, Kazunori ; Hamada, Shigeyuki. / Dissemination of carbapenemase-producing Enterobacteriaceae harbouring bla NDM or bla IMI in local market foods of Yangon, Myanmar. In: Scientific reports. 2019 ; Vol. 9, No. 1.
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