Dissecting the left heart hypoplasia by pluripotent stem cells

Junko Kobayashi, Shunji Sano, Hidemasa Oh

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The genetic background of hypoplastic left heart syndrome (HLHS) is still unknown. Cardiac differentiation from pluripotent stem cells (PSCs) can recapitulate the cardiogenesis in vitro, and PSC technology could be useful to dissect the diseases with the complex mechanisms. In the past few years, some researches were reported to seek the pathogenesis of HLHS by using PSCs. This paper reports the achievements.

Original languageEnglish
Title of host publicationEtiology and Morphogenesis of Congenital Heart Disease
Subtitle of host publicationFrom Gene Function and Cellular Interaction to Morphology
PublisherSpringer Japan
Pages337-339
Number of pages3
ISBN (Electronic)9784431546283
ISBN (Print)9784431546276
DOIs
Publication statusPublished - Jan 1 2016

Keywords

  • Disease modeling
  • Hypoplastic left heart syndrome
  • Pluripotent stem cells

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

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  • Cite this

    Kobayashi, J., Sano, S., & Oh, H. (2016). Dissecting the left heart hypoplasia by pluripotent stem cells. In Etiology and Morphogenesis of Congenital Heart Disease: From Gene Function and Cellular Interaction to Morphology (pp. 337-339). Springer Japan. https://doi.org/10.1007/978-4-431-54628-3_47