Discrepant uptake between fluorine-18 fluorodeoxy glucose and Tc-99m sestamibi in bronchioloalveolar cell carcinoma

Takahiro Higuchi, Syoutoku Tagawa, Naohiro Yoshida, Tsutomu Araki, Taketsugu Tsuchiya, Koutarou Higashi, Junichi Taki, Seigo Kinuya, Kenichi Nakajima, Masatoshi Ikeda, Masanobu Namura, Norihisa Tonami

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Several studies have shown the benefit of fluorine-18 fluorodeoxy glucose (FDG) imaging in the differentiation of solitary pulmonary nodules. The majority of malignant tumor have a higher glucose metabolic rate as compared to benign lesions. However, there is a considerable variety in glucose metabolic rate that depends on the aggressiveness and histological subtype of the tumor. Technetium-99m sestamibi (MIBI) is another tumor imaging agent for SPECT. We present a case of bronchioloalveolar cell carcinoma with a false negative finding in FDG imaging and a positive finding in MIBI imaging. This case clearly indicates that the FDG uptake and MIBI uptake might provide different information regarding characteristics of lung cancer.

Original languageEnglish
Pages (from-to)499-501
Number of pages3
JournalAnnals of nuclear medicine
Volume17
Issue number6
DOIs
Publication statusPublished - Sep 2003
Externally publishedYes

Keywords

  • Bronchioloalveolar cell carcinoma
  • Fluorine-18 fluorodeoxy glucose
  • Lung cancer
  • Myocardial perfusion SPECT
  • Technetium-99m sestamibi

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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    Higuchi, T., Tagawa, S., Yoshida, N., Araki, T., Tsuchiya, T., Higashi, K., Taki, J., Kinuya, S., Nakajima, K., Ikeda, M., Namura, M., & Tonami, N. (2003). Discrepant uptake between fluorine-18 fluorodeoxy glucose and Tc-99m sestamibi in bronchioloalveolar cell carcinoma. Annals of nuclear medicine, 17(6), 499-501. https://doi.org/10.1007/BF03006442