A protein that specifically targets lipid droplets (LDs) was created by connecting two domains of nonstructural protein 4B containing amphipathic helices from hepatitis C virus. We demonstrated its direct targeting and accumulation to the LD surface by time-lapse live cell imaging, comparable to those observed with adipose differentiation-related protein.
- Adipose differentiation-related protein
- Hepatitis C virus
- Lipid droplets
- Nonstructural protein 4B
- Time-lapse imaging
ASJC Scopus subject areas
- Applied Microbiology and Biotechnology