Direct antitumor effect of cepharanthin and combined effect with adriamycin against Ehrlich ascites tumor in mice

Jun-Ichi Asaumi, K. Nishikawa, H. Matsuoka, M. Iwata, S. Kawasaki, Y. Hiraki, K. Nishijima

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Abstract

Direct antitumor effect of cepharanthin (CEP) and the combined effect with adriamycin (ADR), as well as the effect of CEP against body weight loss caused by treatment of ADR were evaluated using ICR mice bearing Ehrlich ascites tumor. Single administration of CEP reduced tumor growth compared to that of the untreated control, but not significantly. However, multiple administration of CEP reduced the tumor growth significantly compared to that of the untreated control (p

Original languageEnglish
Pages (from-to)67-70
Number of pages4
JournalAnticancer Research
Volume15
Issue number1
Publication statusPublished - 1995

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Keywords

  • Adriamycin
  • Cepharanthin
  • In vivo

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Asaumi, J-I., Nishikawa, K., Matsuoka, H., Iwata, M., Kawasaki, S., Hiraki, Y., & Nishijima, K. (1995). Direct antitumor effect of cepharanthin and combined effect with adriamycin against Ehrlich ascites tumor in mice. Anticancer Research, 15(1), 67-70.