Dimeric flavans from gambir and their structural correlations with (+)-catechin

Shoko Taniguchi, Kayo Kuroda, Kou ichi Doi, Masahiro Tanabe, Takashi Shibata, Takashi Yoshida, Tsutomu Hatano

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

We isolated two new flavan dimers, gambirflavan D3 (10) and gambirflavan D4 (12), together with gambiriin A3 (11), from gambir, a hot-water extract of the leaves and young twigs of Uncaria gambir. Because their spectral analyses suggested that they are derived from catechin, we conducted a conversion reaction using (+)-catechin (1) to produce these dimers; another new flavan, gambirflavan D5 (13), was obtained as a product of this reaction. The structural relationship of these dimeric flavans with (+)-catechin (1) is discussed.

Original languageEnglish
Pages (from-to)1171-1180
Number of pages10
JournalHeterocycles
Volume76
Issue number2
DOIs
Publication statusPublished - Nov 1 2008

Keywords

  • Catechin
  • Condensed Tannin
  • Dimeric Flavan
  • Gambir
  • Uncaria gambir

ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

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