Abstract
We isolated two new flavan dimers, gambirflavan D3 (10) and gambirflavan D4 (12), together with gambiriin A3 (11), from gambir, a hot-water extract of the leaves and young twigs of Uncaria gambir. Because their spectral analyses suggested that they are derived from catechin, we conducted a conversion reaction using (+)-catechin (1) to produce these dimers; another new flavan, gambirflavan D5 (13), was obtained as a product of this reaction. The structural relationship of these dimeric flavans with (+)-catechin (1) is discussed.
Original language | English |
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Pages (from-to) | 1171-1180 |
Number of pages | 10 |
Journal | Heterocycles |
Volume | 76 |
Issue number | 2 |
DOIs | |
Publication status | Published - Nov 1 2008 |
Keywords
- Catechin
- Condensed Tannin
- Dimeric Flavan
- Gambir
- Uncaria gambir
ASJC Scopus subject areas
- Analytical Chemistry
- Pharmacology
- Organic Chemistry