Abstract
We isolated two new flavan dimers, gambirflavan D3 (10) and gambirflavan D4 (12), together with gambiriin A3 (11), from gambir, a hot-water extract of the leaves and young twigs of Uncaria gambir. Because their spectral analyses suggested that they are derived from catechin, we conducted a conversion reaction using (+)-catechin (1) to produce these dimers; another new flavan, gambirflavan D5 (13), was obtained as a product of this reaction. The structural relationship of these dimeric flavans with (+)-catechin (1) is discussed.
| Original language | English |
|---|---|
| Pages (from-to) | 1171-1180 |
| Number of pages | 10 |
| Journal | Heterocycles |
| Volume | 76 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Nov 1 2008 |
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Keywords
- Catechin
- Condensed Tannin
- Dimeric Flavan
- Gambir
- Uncaria gambir
ASJC Scopus subject areas
- Analytical Chemistry
- Organic Chemistry
- Pharmacology
Cite this
Dimeric flavans from gambir and their structural correlations with (+)-catechin. / Taniguchi, Shoko; Kuroda, Kayo; Doi, Kou ichi; Tanabe, Masahiro; Shibata, Takashi; Yoshida, Takashi; Hatano, Tsutomu.
In: Heterocycles, Vol. 76, No. 2, 01.11.2008, p. 1171-1180.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Dimeric flavans from gambir and their structural correlations with (+)-catechin
AU - Taniguchi, Shoko
AU - Kuroda, Kayo
AU - Doi, Kou ichi
AU - Tanabe, Masahiro
AU - Shibata, Takashi
AU - Yoshida, Takashi
AU - Hatano, Tsutomu
PY - 2008/11/1
Y1 - 2008/11/1
N2 - We isolated two new flavan dimers, gambirflavan D3 (10) and gambirflavan D4 (12), together with gambiriin A3 (11), from gambir, a hot-water extract of the leaves and young twigs of Uncaria gambir. Because their spectral analyses suggested that they are derived from catechin, we conducted a conversion reaction using (+)-catechin (1) to produce these dimers; another new flavan, gambirflavan D5 (13), was obtained as a product of this reaction. The structural relationship of these dimeric flavans with (+)-catechin (1) is discussed.
AB - We isolated two new flavan dimers, gambirflavan D3 (10) and gambirflavan D4 (12), together with gambiriin A3 (11), from gambir, a hot-water extract of the leaves and young twigs of Uncaria gambir. Because their spectral analyses suggested that they are derived from catechin, we conducted a conversion reaction using (+)-catechin (1) to produce these dimers; another new flavan, gambirflavan D5 (13), was obtained as a product of this reaction. The structural relationship of these dimeric flavans with (+)-catechin (1) is discussed.
KW - Catechin
KW - Condensed Tannin
KW - Dimeric Flavan
KW - Gambir
KW - Uncaria gambir
UR - http://www.scopus.com/inward/record.url?scp=61349187084&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=61349187084&partnerID=8YFLogxK
U2 - 10.3987/COM-08-S(N)76
DO - 10.3987/COM-08-S(N)76
M3 - Article
AN - SCOPUS:61349187084
VL - 76
SP - 1171
EP - 1180
JO - Heterocycles
JF - Heterocycles
SN - 0385-5414
IS - 2
ER -