Dimeric flavans from gambir and their structural correlations with (+)-catechin

Shoko Taniguchi; Kayo Kuroda; Kou ichi Doi; Masahiro Tanabe; Takashi Shibata; Takashi Yoshida; Tsutomu Hatano

doi:10.3987/COM-08-S(N)76

Dimeric flavans from gambir and their structural correlations with (+)-catechin

Shoko Taniguchi, Kayo Kuroda, Kou ichi Doi, Masahiro Tanabe, Takashi Shibata, Takashi Yoshida, Tsutomu Hatano

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

We isolated two new flavan dimers, gambirflavan D3 (10) and gambirflavan D4 (12), together with gambiriin A3 (11), from gambir, a hot-water extract of the leaves and young twigs of Uncaria gambir. Because their spectral analyses suggested that they are derived from catechin, we conducted a conversion reaction using (+)-catechin (1) to produce these dimers; another new flavan, gambirflavan D5 (13), was obtained as a product of this reaction. The structural relationship of these dimeric flavans with (+)-catechin (1) is discussed.

Original language	English
Pages (from-to)	1171-1180
Number of pages	10
Journal	Heterocycles
Volume	76
Issue number	2
DOIs	https://doi.org/10.3987/COM-08-S(N)76
Publication status	Published - Nov 1 2008

Keywords

Catechin
Condensed Tannin
Dimeric Flavan
Gambir
Uncaria gambir

ASJC Scopus subject areas

Analytical Chemistry
Pharmacology
Organic Chemistry

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abstract = "We isolated two new flavan dimers, gambirflavan D3 (10) and gambirflavan D4 (12), together with gambiriin A3 (11), from gambir, a hot-water extract of the leaves and young twigs of Uncaria gambir. Because their spectral analyses suggested that they are derived from catechin, we conducted a conversion reaction using (+)-catechin (1) to produce these dimers; another new flavan, gambirflavan D5 (13), was obtained as a product of this reaction. The structural relationship of these dimeric flavans with (+)-catechin (1) is discussed.",

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AU - Taniguchi, Shoko

AU - Kuroda, Kayo

AU - Doi, Kou ichi

AU - Tanabe, Masahiro

AU - Shibata, Takashi

AU - Yoshida, Takashi

AU - Hatano, Tsutomu

PY - 2008/11/1

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N2 - We isolated two new flavan dimers, gambirflavan D3 (10) and gambirflavan D4 (12), together with gambiriin A3 (11), from gambir, a hot-water extract of the leaves and young twigs of Uncaria gambir. Because their spectral analyses suggested that they are derived from catechin, we conducted a conversion reaction using (+)-catechin (1) to produce these dimers; another new flavan, gambirflavan D5 (13), was obtained as a product of this reaction. The structural relationship of these dimeric flavans with (+)-catechin (1) is discussed.

AB - We isolated two new flavan dimers, gambirflavan D3 (10) and gambirflavan D4 (12), together with gambiriin A3 (11), from gambir, a hot-water extract of the leaves and young twigs of Uncaria gambir. Because their spectral analyses suggested that they are derived from catechin, we conducted a conversion reaction using (+)-catechin (1) to produce these dimers; another new flavan, gambirflavan D5 (13), was obtained as a product of this reaction. The structural relationship of these dimeric flavans with (+)-catechin (1) is discussed.

KW - Catechin

KW - Condensed Tannin

KW - Dimeric Flavan

KW - Gambir

KW - Uncaria gambir

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Dimeric flavans from gambir and their structural correlations with (+)-catechin

Abstract

Keywords

ASJC Scopus subject areas

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