Gastric cancer of fundic gland type that is not associated with chronic atrophic gastritis caused by Helicobacter pylori infection has recently been proposed. This cancer emerges at the deep layer of the mucosa and, thus, often invades the submucosal layer at a high rate even when it is small. We report endoscopic characteristics of 6 cases of early gastric cancer of fundic gland type without exposure of cancer glands on the surface. The mean diameter of the lesions was 6.0mm. We found submucosal invasion in 2 cases (400μ and 130μ), and the other four were confined to the mucosal layer. Endoscopically, most of them were small, gradually elevated lesions covered with normal fundic gland gastric mucosa mimicking a fundic gland cyst polyp or a submucosal tumor. There was no irregular change in their surface pattern even under image-enhanced endoscopic observation, but we often observed dilated vessels on their surface (83%). Thus, when we observe dilated vessels on the surface of a small lesion like a fundic gland cyst polyp or submucosal tumor, we should perform biopsy for the possibility of gastric cancer of fundic gland type at its early stage.
|Number of pages||7|
|Publication status||Published - 2015|
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging