Differentiation of benign from malignant nodules by accumulation of Tc- 99m pertechnetate using TI-201 delayed scans

Yoshihiro Okumura, Yoshihiro Takeda, Shuhei Sato, Mituharu Shimizu, Megumi Komatsu, Osamu Honda, Tomio Nakagawa, Harutaka Niiya, Yoshio Hiraki

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Thyroid carcinoma usually is characterized by a nonfunctioning or 'cold' nodule depicted on the Tc-99m scan. Twelve patients with functioning 'hot' thyroid nodules underwent thyroidectomy (nine hemithyroidectomies, two nodulectomies, and one subtotal thyroidectomy). Histologic examination revealed that five patients (42%) had malignant nodules (papillary carcinoma in two and follicular carcinoma in three). Of the seven patients with benign nodules, five had follicular adenoma and two had adenomatous hyperplasia. TI- 201 scanning (early and delayed) was performed at the same time as Tc-99m scanning. Only one of the seven benign nodules showed accumulation on the delayed TI-201 scan, whereas all five malignant nodules showed accumulation. The delayed TI-201 scan is useful for the differentiation of benign from malignant nodules that show accumulation of Tc-99m pertechnetate.

Original languageEnglish
Pages (from-to)514-516
Number of pages3
JournalClinical Nuclear Medicine
Volume23
Issue number8
DOIs
Publication statusPublished - Aug 1 1998

Keywords

  • TI-201
  • Tc-99m Pertechnetate
  • Thyroid Nodule

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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