Differentiation of benign from malignant nodules by accumulation of Tc- 99m pertechnetate using TI-201 delayed scans

Yoshihiro Okumura, Yoshihiro Takeda, Shuhei Sato, Mituharu Shimizu, Megumi Komatsu, Osamu Honda, Tomio Nakagawa, Harutaka Niiya, Yoshio Hiraki

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Thyroid carcinoma usually is characterized by a nonfunctioning or 'cold' nodule depicted on the Tc-99m scan. Twelve patients with functioning 'hot' thyroid nodules underwent thyroidectomy (nine hemithyroidectomies, two nodulectomies, and one subtotal thyroidectomy). Histologic examination revealed that five patients (42%) had malignant nodules (papillary carcinoma in two and follicular carcinoma in three). Of the seven patients with benign nodules, five had follicular adenoma and two had adenomatous hyperplasia. TI- 201 scanning (early and delayed) was performed at the same time as Tc-99m scanning. Only one of the seven benign nodules showed accumulation on the delayed TI-201 scan, whereas all five malignant nodules showed accumulation. The delayed TI-201 scan is useful for the differentiation of benign from malignant nodules that show accumulation of Tc-99m pertechnetate.

Original languageEnglish
Pages (from-to)514-516
Number of pages3
JournalClinical Nuclear Medicine
Volume23
Issue number8
DOIs
Publication statusPublished - Aug 1998

Fingerprint

Sodium Pertechnetate Tc 99m
Thyroidectomy
Thyroid Nodule
Papillary Carcinoma
Thyroid Neoplasms
Adenoma
Hyperplasia
Carcinoma

Keywords

  • Tc-99m Pertechnetate
  • Thyroid Nodule
  • TI-201

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Differentiation of benign from malignant nodules by accumulation of Tc- 99m pertechnetate using TI-201 delayed scans. / Okumura, Yoshihiro; Takeda, Yoshihiro; Sato, Shuhei; Shimizu, Mituharu; Komatsu, Megumi; Honda, Osamu; Nakagawa, Tomio; Niiya, Harutaka; Hiraki, Yoshio.

In: Clinical Nuclear Medicine, Vol. 23, No. 8, 08.1998, p. 514-516.

Research output: Contribution to journalArticle

Okumura, Yoshihiro ; Takeda, Yoshihiro ; Sato, Shuhei ; Shimizu, Mituharu ; Komatsu, Megumi ; Honda, Osamu ; Nakagawa, Tomio ; Niiya, Harutaka ; Hiraki, Yoshio. / Differentiation of benign from malignant nodules by accumulation of Tc- 99m pertechnetate using TI-201 delayed scans. In: Clinical Nuclear Medicine. 1998 ; Vol. 23, No. 8. pp. 514-516.
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