TY - JOUR
T1 - Differentiation of benign from malignant nodules by accumulation of Tc- 99m pertechnetate using TI-201 delayed scans
AU - Okumura, Yoshihiro
AU - Takeda, Yoshihiro
AU - Sato, Shuhei
AU - Shimizu, Mituharu
AU - Komatsu, Megumi
AU - Honda, Osamu
AU - Nakagawa, Tomio
AU - Niiya, Harutaka
AU - Hiraki, Yoshio
PY - 1998/8/1
Y1 - 1998/8/1
N2 - Thyroid carcinoma usually is characterized by a nonfunctioning or 'cold' nodule depicted on the Tc-99m scan. Twelve patients with functioning 'hot' thyroid nodules underwent thyroidectomy (nine hemithyroidectomies, two nodulectomies, and one subtotal thyroidectomy). Histologic examination revealed that five patients (42%) had malignant nodules (papillary carcinoma in two and follicular carcinoma in three). Of the seven patients with benign nodules, five had follicular adenoma and two had adenomatous hyperplasia. TI- 201 scanning (early and delayed) was performed at the same time as Tc-99m scanning. Only one of the seven benign nodules showed accumulation on the delayed TI-201 scan, whereas all five malignant nodules showed accumulation. The delayed TI-201 scan is useful for the differentiation of benign from malignant nodules that show accumulation of Tc-99m pertechnetate.
AB - Thyroid carcinoma usually is characterized by a nonfunctioning or 'cold' nodule depicted on the Tc-99m scan. Twelve patients with functioning 'hot' thyroid nodules underwent thyroidectomy (nine hemithyroidectomies, two nodulectomies, and one subtotal thyroidectomy). Histologic examination revealed that five patients (42%) had malignant nodules (papillary carcinoma in two and follicular carcinoma in three). Of the seven patients with benign nodules, five had follicular adenoma and two had adenomatous hyperplasia. TI- 201 scanning (early and delayed) was performed at the same time as Tc-99m scanning. Only one of the seven benign nodules showed accumulation on the delayed TI-201 scan, whereas all five malignant nodules showed accumulation. The delayed TI-201 scan is useful for the differentiation of benign from malignant nodules that show accumulation of Tc-99m pertechnetate.
KW - TI-201
KW - Tc-99m Pertechnetate
KW - Thyroid Nodule
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U2 - 10.1097/00003072-199808000-00004
DO - 10.1097/00003072-199808000-00004
M3 - Article
C2 - 9712383
AN - SCOPUS:0031714636
VL - 23
SP - 514
EP - 516
JO - Clinical Nuclear Medicine
JF - Clinical Nuclear Medicine
SN - 0363-9762
IS - 8
ER -