Differential seroprevalences of hepatitis C virus, hepatitis B virus and human immunodeficiency virus among intravenous drug users, commercial sex workers and patients with sexually transmitted diseases in Chiang Mai, Thailand

Kazuhisa Taketa, Satoru Ikeda, Narufumi Suganuma, Kannika Phornphutkul, Supatra Peerakome, Kriegsak Sitvacharanum, Jaroon Jittiwutikarn

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

To elucidate the differences in the mode of transmission of three blood-borne viruses, hepatitis C virus (HCV), hepatitis B virus (HBV) and human immunodeficiency virus (HIV), under comparable conditions of study, we analyzed the prevalences of anti-HCV antibodies (anti-HCV), anti-HBV core antibodies (anti-HBc), HBV surface antigen (HBsAg) and anti-HIV antibodies (anti-HIV) in different risk populations in Chiang Mai, Thailand, where the prevalence of HIV infection is high. The subjects consisted of 98 intravenous drug users (IVDU), 100 commercial sex workers (CSW) and 50 male patients with sexually transmitted diseases (STD). In IVDU the prevalence of anti-HCV was the highest (85%), followed by anti-HBc (77%) and anti-HIV (46%), whereas in CSW and STD the prevalence of anti-HCV was 2 and 0%, respectively, that of anti-HBc 69 and 64%, respectively, and that of anti-HIV 11 and 14%, respectively. The prevalence of anti-HBc minus that of HBsAg, representing horizontal transmission of HBV, was similar for IVDU (63%), CSW (58%) and STD (64%). Thus, HCV is mainly transmitted by blood contact, HIV primarily by blood contact rather than by sexual contact, and HBV equally readily by blood or sexual contact. These findings were supported by the results of logistic regression analysis.

Original languageEnglish
Pages (from-to)6-12
Number of pages7
JournalHepatology Research
Volume27
Issue number1
DOIs
Publication statusPublished - Sep 1 2003

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Sex Workers
Seroepidemiologic Studies
Thailand
Sexually Transmitted Diseases
Drug Users
Hepatitis B virus
Hepacivirus
HIV
Anti-Idiotypic Antibodies
Hepatitis B Antibodies
Hepatitis C Antibodies
Antibodies
Virus Diseases
Surface Antigens
Hepatitis B Surface Antigens
Cross-Sectional Studies
Logistic Models
Regression Analysis
Viruses
Population

Keywords

  • Commercial sex workers
  • Hepatitis B virus
  • Hepatitis C virus
  • Human immunodeficiency virus
  • Intravenous drug users
  • Seroprevalence
  • Sexually transmitted diseases

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Differential seroprevalences of hepatitis C virus, hepatitis B virus and human immunodeficiency virus among intravenous drug users, commercial sex workers and patients with sexually transmitted diseases in Chiang Mai, Thailand. / Taketa, Kazuhisa; Ikeda, Satoru; Suganuma, Narufumi; Phornphutkul, Kannika; Peerakome, Supatra; Sitvacharanum, Kriegsak; Jittiwutikarn, Jaroon.

In: Hepatology Research, Vol. 27, No. 1, 01.09.2003, p. 6-12.

Research output: Contribution to journalArticle

Taketa, Kazuhisa ; Ikeda, Satoru ; Suganuma, Narufumi ; Phornphutkul, Kannika ; Peerakome, Supatra ; Sitvacharanum, Kriegsak ; Jittiwutikarn, Jaroon. / Differential seroprevalences of hepatitis C virus, hepatitis B virus and human immunodeficiency virus among intravenous drug users, commercial sex workers and patients with sexually transmitted diseases in Chiang Mai, Thailand. In: Hepatology Research. 2003 ; Vol. 27, No. 1. pp. 6-12.
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abstract = "To elucidate the differences in the mode of transmission of three blood-borne viruses, hepatitis C virus (HCV), hepatitis B virus (HBV) and human immunodeficiency virus (HIV), under comparable conditions of study, we analyzed the prevalences of anti-HCV antibodies (anti-HCV), anti-HBV core antibodies (anti-HBc), HBV surface antigen (HBsAg) and anti-HIV antibodies (anti-HIV) in different risk populations in Chiang Mai, Thailand, where the prevalence of HIV infection is high. The subjects consisted of 98 intravenous drug users (IVDU), 100 commercial sex workers (CSW) and 50 male patients with sexually transmitted diseases (STD). In IVDU the prevalence of anti-HCV was the highest (85{\%}), followed by anti-HBc (77{\%}) and anti-HIV (46{\%}), whereas in CSW and STD the prevalence of anti-HCV was 2 and 0{\%}, respectively, that of anti-HBc 69 and 64{\%}, respectively, and that of anti-HIV 11 and 14{\%}, respectively. The prevalence of anti-HBc minus that of HBsAg, representing horizontal transmission of HBV, was similar for IVDU (63{\%}), CSW (58{\%}) and STD (64{\%}). Thus, HCV is mainly transmitted by blood contact, HIV primarily by blood contact rather than by sexual contact, and HBV equally readily by blood or sexual contact. These findings were supported by the results of logistic regression analysis.",
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