Abstract
To elucidate the differences in the mode of transmission of three blood-borne viruses, hepatitis C virus (HCV), hepatitis B virus (HBV) and human immunodeficiency virus (HIV), under comparable conditions of study, we analyzed the prevalences of anti-HCV antibodies (anti-HCV), anti-HBV core antibodies (anti-HBc), HBV surface antigen (HBsAg) and anti-HIV antibodies (anti-HIV) in different risk populations in Chiang Mai, Thailand, where the prevalence of HIV infection is high. The subjects consisted of 98 intravenous drug users (IVDU), 100 commercial sex workers (CSW) and 50 male patients with sexually transmitted diseases (STD). In IVDU the prevalence of anti-HCV was the highest (85%), followed by anti-HBc (77%) and anti-HIV (46%), whereas in CSW and STD the prevalence of anti-HCV was 2 and 0%, respectively, that of anti-HBc 69 and 64%, respectively, and that of anti-HIV 11 and 14%, respectively. The prevalence of anti-HBc minus that of HBsAg, representing horizontal transmission of HBV, was similar for IVDU (63%), CSW (58%) and STD (64%). Thus, HCV is mainly transmitted by blood contact, HIV primarily by blood contact rather than by sexual contact, and HBV equally readily by blood or sexual contact. These findings were supported by the results of logistic regression analysis.
| Original language | English |
|---|---|
| Pages (from-to) | 6-12 |
| Number of pages | 7 |
| Journal | Hepatology Research |
| Volume | 27 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Sep 1 2003 |
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Keywords
- Commercial sex workers
- Hepatitis B virus
- Hepatitis C virus
- Human immunodeficiency virus
- Intravenous drug users
- Seroprevalence
- Sexually transmitted diseases
ASJC Scopus subject areas
- Gastroenterology
Cite this
Differential seroprevalences of hepatitis C virus, hepatitis B virus and human immunodeficiency virus among intravenous drug users, commercial sex workers and patients with sexually transmitted diseases in Chiang Mai, Thailand. / Taketa, Kazuhisa; Ikeda, Satoru; Suganuma, Narufumi; Phornphutkul, Kannika; Peerakome, Supatra; Sitvacharanum, Kriegsak; Jittiwutikarn, Jaroon.
In: Hepatology Research, Vol. 27, No. 1, 01.09.2003, p. 6-12.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Differential seroprevalences of hepatitis C virus, hepatitis B virus and human immunodeficiency virus among intravenous drug users, commercial sex workers and patients with sexually transmitted diseases in Chiang Mai, Thailand
AU - Taketa, Kazuhisa
AU - Ikeda, Satoru
AU - Suganuma, Narufumi
AU - Phornphutkul, Kannika
AU - Peerakome, Supatra
AU - Sitvacharanum, Kriegsak
AU - Jittiwutikarn, Jaroon
PY - 2003/9/1
Y1 - 2003/9/1
N2 - To elucidate the differences in the mode of transmission of three blood-borne viruses, hepatitis C virus (HCV), hepatitis B virus (HBV) and human immunodeficiency virus (HIV), under comparable conditions of study, we analyzed the prevalences of anti-HCV antibodies (anti-HCV), anti-HBV core antibodies (anti-HBc), HBV surface antigen (HBsAg) and anti-HIV antibodies (anti-HIV) in different risk populations in Chiang Mai, Thailand, where the prevalence of HIV infection is high. The subjects consisted of 98 intravenous drug users (IVDU), 100 commercial sex workers (CSW) and 50 male patients with sexually transmitted diseases (STD). In IVDU the prevalence of anti-HCV was the highest (85%), followed by anti-HBc (77%) and anti-HIV (46%), whereas in CSW and STD the prevalence of anti-HCV was 2 and 0%, respectively, that of anti-HBc 69 and 64%, respectively, and that of anti-HIV 11 and 14%, respectively. The prevalence of anti-HBc minus that of HBsAg, representing horizontal transmission of HBV, was similar for IVDU (63%), CSW (58%) and STD (64%). Thus, HCV is mainly transmitted by blood contact, HIV primarily by blood contact rather than by sexual contact, and HBV equally readily by blood or sexual contact. These findings were supported by the results of logistic regression analysis.
AB - To elucidate the differences in the mode of transmission of three blood-borne viruses, hepatitis C virus (HCV), hepatitis B virus (HBV) and human immunodeficiency virus (HIV), under comparable conditions of study, we analyzed the prevalences of anti-HCV antibodies (anti-HCV), anti-HBV core antibodies (anti-HBc), HBV surface antigen (HBsAg) and anti-HIV antibodies (anti-HIV) in different risk populations in Chiang Mai, Thailand, where the prevalence of HIV infection is high. The subjects consisted of 98 intravenous drug users (IVDU), 100 commercial sex workers (CSW) and 50 male patients with sexually transmitted diseases (STD). In IVDU the prevalence of anti-HCV was the highest (85%), followed by anti-HBc (77%) and anti-HIV (46%), whereas in CSW and STD the prevalence of anti-HCV was 2 and 0%, respectively, that of anti-HBc 69 and 64%, respectively, and that of anti-HIV 11 and 14%, respectively. The prevalence of anti-HBc minus that of HBsAg, representing horizontal transmission of HBV, was similar for IVDU (63%), CSW (58%) and STD (64%). Thus, HCV is mainly transmitted by blood contact, HIV primarily by blood contact rather than by sexual contact, and HBV equally readily by blood or sexual contact. These findings were supported by the results of logistic regression analysis.
KW - Commercial sex workers
KW - Hepatitis B virus
KW - Hepatitis C virus
KW - Human immunodeficiency virus
KW - Intravenous drug users
KW - Seroprevalence
KW - Sexually transmitted diseases
UR - http://www.scopus.com/inward/record.url?scp=0141717254&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0141717254&partnerID=8YFLogxK
U2 - 10.1016/S1386-6346(03)00163-3
DO - 10.1016/S1386-6346(03)00163-3
M3 - Article
AN - SCOPUS:0141717254
VL - 27
SP - 6
EP - 12
JO - Hepatology Research
JF - Hepatology Research
SN - 1386-6346
IS - 1
ER -