Abstract
To evaluate the role of the masticatory area in the cerebral cortex in the masticatory-salivary reflex, we investigated submandibular salivary secretion, jaw-movement trajectory and electromyographic activity of the jaw-opener (digastric) and jaw-closer (masseter) muscles evoked by repetitive electrical stimulation of the cortical masticatory area in anesthetized rats. Rats have two cortical masticatory areas: the anterior area (A-area) in the orofacial motor cortex, and the posterior area (P-area) in the insular cortex. Our defined P-area extended more caudally than the previous reported one. P-area stimulation induced vigorous salivary secretion (about 20 μl/min) and rhythmical jaw movements (3-4 Hz) resembling masticatory movements. Salivary flow persisted even after minimizing jaw movements by curarization. A-area stimulation induced small and fast rhythmical jaw movements (6-8 Hz) resembling licking of solutions, but not salivary secretion. These findings suggest that P-area controls salivary secretion as well as mastication, and may be involved in the masticatory-salivary reflex.
| Original language | English |
|---|---|
| Pages (from-to) | 200-208 |
| Number of pages | 9 |
| Journal | Brain Research |
| Volume | 1543 |
| DOIs | |
| Publication status | Published - Jan 16 2014 |
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Keywords
- Cerebral cortex
- EMG
- Jaw movements
- Rat
- Salivary secretion
ASJC Scopus subject areas
- Neuroscience(all)
- Clinical Neurology
- Developmental Biology
- Molecular Biology
Cite this
Differential involvement of two cortical masticatory areas in submandibular salivary secretion in rats. / Maeda, Naoto; Kobashi, Motoi; Mitoh, Yoshihiro; Fujita, Masako; Minagi, Shogo; Matsuo, Ryuji.
In: Brain Research, Vol. 1543, 16.01.2014, p. 200-208.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Differential involvement of two cortical masticatory areas in submandibular salivary secretion in rats
AU - Maeda, Naoto
AU - Kobashi, Motoi
AU - Mitoh, Yoshihiro
AU - Fujita, Masako
AU - Minagi, Shogo
AU - Matsuo, Ryuji
PY - 2014/1/16
Y1 - 2014/1/16
N2 - To evaluate the role of the masticatory area in the cerebral cortex in the masticatory-salivary reflex, we investigated submandibular salivary secretion, jaw-movement trajectory and electromyographic activity of the jaw-opener (digastric) and jaw-closer (masseter) muscles evoked by repetitive electrical stimulation of the cortical masticatory area in anesthetized rats. Rats have two cortical masticatory areas: the anterior area (A-area) in the orofacial motor cortex, and the posterior area (P-area) in the insular cortex. Our defined P-area extended more caudally than the previous reported one. P-area stimulation induced vigorous salivary secretion (about 20 μl/min) and rhythmical jaw movements (3-4 Hz) resembling masticatory movements. Salivary flow persisted even after minimizing jaw movements by curarization. A-area stimulation induced small and fast rhythmical jaw movements (6-8 Hz) resembling licking of solutions, but not salivary secretion. These findings suggest that P-area controls salivary secretion as well as mastication, and may be involved in the masticatory-salivary reflex.
AB - To evaluate the role of the masticatory area in the cerebral cortex in the masticatory-salivary reflex, we investigated submandibular salivary secretion, jaw-movement trajectory and electromyographic activity of the jaw-opener (digastric) and jaw-closer (masseter) muscles evoked by repetitive electrical stimulation of the cortical masticatory area in anesthetized rats. Rats have two cortical masticatory areas: the anterior area (A-area) in the orofacial motor cortex, and the posterior area (P-area) in the insular cortex. Our defined P-area extended more caudally than the previous reported one. P-area stimulation induced vigorous salivary secretion (about 20 μl/min) and rhythmical jaw movements (3-4 Hz) resembling masticatory movements. Salivary flow persisted even after minimizing jaw movements by curarization. A-area stimulation induced small and fast rhythmical jaw movements (6-8 Hz) resembling licking of solutions, but not salivary secretion. These findings suggest that P-area controls salivary secretion as well as mastication, and may be involved in the masticatory-salivary reflex.
KW - Cerebral cortex
KW - EMG
KW - Jaw movements
KW - Rat
KW - Salivary secretion
UR - http://www.scopus.com/inward/record.url?scp=84891740268&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84891740268&partnerID=8YFLogxK
U2 - 10.1016/j.brainres.2013.11.024
DO - 10.1016/j.brainres.2013.11.024
M3 - Article
C2 - 24309141
AN - SCOPUS:84891740268
VL - 1543
SP - 200
EP - 208
JO - Brain Research
JF - Brain Research
SN - 0006-8993
ER -