Differential expression of HR38 in the mushroom bodies of the honeybee brain depends on the caste and division of labor

Yurika Yamazaki; Kenichi Shirai; Rajib Kumar Paul; Tomoko Fujiyuki; Akiko Wakamoto; Hideaki Takeuchi; Takeo Kubo

doi:10.1016/j.febslet.2006.04.016

Differential expression of HR38 in the mushroom bodies of the honeybee brain depends on the caste and division of labor

Yurika Yamazaki, Kenichi Shirai, Rajib Kumar Paul, Tomoko Fujiyuki, Akiko Wakamoto, Hideaki Takeuchi, Takeo Kubo

Research output: Contribution to journal › Article › peer-review

57 Citations (Scopus)

Abstract

We used a cDNA microarray to identify genes expressed in a caste (worker)- and division of labor (nurse bees or foragers)-dependent manner in the honeybee brain. Among the identified genes, one encoded a putative orphan receptor (HR38) homologue that mediates ecdysteroid-signaling. Real-time reverse transcription-polymerase chain reaction indicated that expression of this gene is higher in forager brains, as compared to nurse bees and queens. In the forager brain, expression was concentrated in a subset of the mushroom body neurons, suggesting that ecdysteroid-signaling in the mushroom bodies might be involved in the division of labor of the workers.

Original language	English
Pages (from-to)	2667-2670
Number of pages	4
Journal	FEBS Letters
Volume	580
Issue number	11
DOIs	https://doi.org/10.1016/j.febslet.2006.04.016
Publication status	Published - May 15 2006
Externally published	Yes

Keywords

Ecdysteroid
HR38
Honeybee
Microarray
Mushroom body
Orphan receptor

ASJC Scopus subject areas

Biophysics
Structural Biology
Biochemistry
Molecular Biology
Genetics
Cell Biology

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10.1016/j.febslet.2006.04.016

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title = "Differential expression of HR38 in the mushroom bodies of the honeybee brain depends on the caste and division of labor",

abstract = "We used a cDNA microarray to identify genes expressed in a caste (worker)- and division of labor (nurse bees or foragers)-dependent manner in the honeybee brain. Among the identified genes, one encoded a putative orphan receptor (HR38) homologue that mediates ecdysteroid-signaling. Real-time reverse transcription-polymerase chain reaction indicated that expression of this gene is higher in forager brains, as compared to nurse bees and queens. In the forager brain, expression was concentrated in a subset of the mushroom body neurons, suggesting that ecdysteroid-signaling in the mushroom bodies might be involved in the division of labor of the workers.",

keywords = "Ecdysteroid, HR38, Honeybee, Microarray, Mushroom body, Orphan receptor",

author = "Yurika Yamazaki and Kenichi Shirai and Paul, {Rajib Kumar} and Tomoko Fujiyuki and Akiko Wakamoto and Hideaki Takeuchi and Takeo Kubo",

note = "Funding Information: This work was supported by the Program for Promotion of Basic Research Activities for Innovative Bioscience and Grant-in-Aid from the Ministry of Education, Science, Sports, and Culture of Japan.",

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doi = "10.1016/j.febslet.2006.04.016",

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AU - Yamazaki, Yurika

AU - Shirai, Kenichi

AU - Paul, Rajib Kumar

AU - Fujiyuki, Tomoko

AU - Wakamoto, Akiko

AU - Takeuchi, Hideaki

AU - Kubo, Takeo

N1 - Funding Information: This work was supported by the Program for Promotion of Basic Research Activities for Innovative Bioscience and Grant-in-Aid from the Ministry of Education, Science, Sports, and Culture of Japan.

PY - 2006/5/15

Y1 - 2006/5/15

N2 - We used a cDNA microarray to identify genes expressed in a caste (worker)- and division of labor (nurse bees or foragers)-dependent manner in the honeybee brain. Among the identified genes, one encoded a putative orphan receptor (HR38) homologue that mediates ecdysteroid-signaling. Real-time reverse transcription-polymerase chain reaction indicated that expression of this gene is higher in forager brains, as compared to nurse bees and queens. In the forager brain, expression was concentrated in a subset of the mushroom body neurons, suggesting that ecdysteroid-signaling in the mushroom bodies might be involved in the division of labor of the workers.

AB - We used a cDNA microarray to identify genes expressed in a caste (worker)- and division of labor (nurse bees or foragers)-dependent manner in the honeybee brain. Among the identified genes, one encoded a putative orphan receptor (HR38) homologue that mediates ecdysteroid-signaling. Real-time reverse transcription-polymerase chain reaction indicated that expression of this gene is higher in forager brains, as compared to nurse bees and queens. In the forager brain, expression was concentrated in a subset of the mushroom body neurons, suggesting that ecdysteroid-signaling in the mushroom bodies might be involved in the division of labor of the workers.

KW - Ecdysteroid

KW - HR38

KW - Honeybee

KW - Microarray

KW - Mushroom body

KW - Orphan receptor

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ER -

Differential expression of HR38 in the mushroom bodies of the honeybee brain depends on the caste and division of labor

Abstract

Keywords

ASJC Scopus subject areas

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