Differential expression of HR38 in the mushroom bodies of the honeybee brain depends on the caste and division of labor

Yurika Yamazaki, Kenichi Shirai, Rajib Kumar Paul, Tomoko Fujiyuki, Akiko Wakamoto, Hideaki Takeuchi, Takeo Kubo

Research output: Contribution to journalArticle

55 Citations (Scopus)

Abstract

We used a cDNA microarray to identify genes expressed in a caste (worker)- and division of labor (nurse bees or foragers)-dependent manner in the honeybee brain. Among the identified genes, one encoded a putative orphan receptor (HR38) homologue that mediates ecdysteroid-signaling. Real-time reverse transcription-polymerase chain reaction indicated that expression of this gene is higher in forager brains, as compared to nurse bees and queens. In the forager brain, expression was concentrated in a subset of the mushroom body neurons, suggesting that ecdysteroid-signaling in the mushroom bodies might be involved in the division of labor of the workers.

Original languageEnglish
Pages (from-to)2667-2670
Number of pages4
JournalFEBS Letters
Volume580
Issue number11
DOIs
Publication statusPublished - May 15 2006
Externally publishedYes

Keywords

  • Ecdysteroid
  • HR38
  • Honeybee
  • Microarray
  • Mushroom body
  • Orphan receptor

ASJC Scopus subject areas

  • Biophysics
  • Structural Biology
  • Biochemistry
  • Molecular Biology
  • Genetics
  • Cell Biology

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