Differential expression of HR38 in the mushroom bodies of the honeybee brain depends on the caste and division of labor

Yurika Yamazaki, Kenichi Shirai, Rajib Kumar Paul, Tomoko Fujiyuki, Akiko Wakamoto, Hideaki Takeuchi, Takeo Kubo

Research output: Contribution to journalArticle

52 Citations (Scopus)

Abstract

We used a cDNA microarray to identify genes expressed in a caste (worker)- and division of labor (nurse bees or foragers)-dependent manner in the honeybee brain. Among the identified genes, one encoded a putative orphan receptor (HR38) homologue that mediates ecdysteroid-signaling. Real-time reverse transcription-polymerase chain reaction indicated that expression of this gene is higher in forager brains, as compared to nurse bees and queens. In the forager brain, expression was concentrated in a subset of the mushroom body neurons, suggesting that ecdysteroid-signaling in the mushroom bodies might be involved in the division of labor of the workers.

Original languageEnglish
Pages (from-to)2667-2670
Number of pages4
JournalFEBS Letters
Volume580
Issue number11
DOIs
Publication statusPublished - May 15 2006
Externally publishedYes

Fingerprint

Mushroom Bodies
Social Class
Ecdysteroids
Brain
Genes
Bees
Personnel
Nurses
Polymerase chain reaction
Transcription
Microarrays
Oligonucleotide Array Sequence Analysis
Reverse Transcription
Neurons
Complementary DNA
Gene Expression
Polymerase Chain Reaction

Keywords

  • Ecdysteroid
  • Honeybee
  • HR38
  • Microarray
  • Mushroom body
  • Orphan receptor

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

Cite this

Differential expression of HR38 in the mushroom bodies of the honeybee brain depends on the caste and division of labor. / Yamazaki, Yurika; Shirai, Kenichi; Paul, Rajib Kumar; Fujiyuki, Tomoko; Wakamoto, Akiko; Takeuchi, Hideaki; Kubo, Takeo.

In: FEBS Letters, Vol. 580, No. 11, 15.05.2006, p. 2667-2670.

Research output: Contribution to journalArticle

Yamazaki, Yurika ; Shirai, Kenichi ; Paul, Rajib Kumar ; Fujiyuki, Tomoko ; Wakamoto, Akiko ; Takeuchi, Hideaki ; Kubo, Takeo. / Differential expression of HR38 in the mushroom bodies of the honeybee brain depends on the caste and division of labor. In: FEBS Letters. 2006 ; Vol. 580, No. 11. pp. 2667-2670.
@article{b12b5ac717554cbcbfd51db58541c121,
title = "Differential expression of HR38 in the mushroom bodies of the honeybee brain depends on the caste and division of labor",
abstract = "We used a cDNA microarray to identify genes expressed in a caste (worker)- and division of labor (nurse bees or foragers)-dependent manner in the honeybee brain. Among the identified genes, one encoded a putative orphan receptor (HR38) homologue that mediates ecdysteroid-signaling. Real-time reverse transcription-polymerase chain reaction indicated that expression of this gene is higher in forager brains, as compared to nurse bees and queens. In the forager brain, expression was concentrated in a subset of the mushroom body neurons, suggesting that ecdysteroid-signaling in the mushroom bodies might be involved in the division of labor of the workers.",
keywords = "Ecdysteroid, Honeybee, HR38, Microarray, Mushroom body, Orphan receptor",
author = "Yurika Yamazaki and Kenichi Shirai and Paul, {Rajib Kumar} and Tomoko Fujiyuki and Akiko Wakamoto and Hideaki Takeuchi and Takeo Kubo",
year = "2006",
month = "5",
day = "15",
doi = "10.1016/j.febslet.2006.04.016",
language = "English",
volume = "580",
pages = "2667--2670",
journal = "FEBS Letters",
issn = "0014-5793",
publisher = "Elsevier",
number = "11",

}

TY - JOUR

T1 - Differential expression of HR38 in the mushroom bodies of the honeybee brain depends on the caste and division of labor

AU - Yamazaki, Yurika

AU - Shirai, Kenichi

AU - Paul, Rajib Kumar

AU - Fujiyuki, Tomoko

AU - Wakamoto, Akiko

AU - Takeuchi, Hideaki

AU - Kubo, Takeo

PY - 2006/5/15

Y1 - 2006/5/15

N2 - We used a cDNA microarray to identify genes expressed in a caste (worker)- and division of labor (nurse bees or foragers)-dependent manner in the honeybee brain. Among the identified genes, one encoded a putative orphan receptor (HR38) homologue that mediates ecdysteroid-signaling. Real-time reverse transcription-polymerase chain reaction indicated that expression of this gene is higher in forager brains, as compared to nurse bees and queens. In the forager brain, expression was concentrated in a subset of the mushroom body neurons, suggesting that ecdysteroid-signaling in the mushroom bodies might be involved in the division of labor of the workers.

AB - We used a cDNA microarray to identify genes expressed in a caste (worker)- and division of labor (nurse bees or foragers)-dependent manner in the honeybee brain. Among the identified genes, one encoded a putative orphan receptor (HR38) homologue that mediates ecdysteroid-signaling. Real-time reverse transcription-polymerase chain reaction indicated that expression of this gene is higher in forager brains, as compared to nurse bees and queens. In the forager brain, expression was concentrated in a subset of the mushroom body neurons, suggesting that ecdysteroid-signaling in the mushroom bodies might be involved in the division of labor of the workers.

KW - Ecdysteroid

KW - Honeybee

KW - HR38

KW - Microarray

KW - Mushroom body

KW - Orphan receptor

UR - http://www.scopus.com/inward/record.url?scp=33646188505&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33646188505&partnerID=8YFLogxK

U2 - 10.1016/j.febslet.2006.04.016

DO - 10.1016/j.febslet.2006.04.016

M3 - Article

C2 - 16647071

AN - SCOPUS:33646188505

VL - 580

SP - 2667

EP - 2670

JO - FEBS Letters

JF - FEBS Letters

SN - 0014-5793

IS - 11

ER -