Diagnostic value of MRI for odontogenic tumours

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Objectives: To evaluate the diagnostic value of MRI for odontogenic tumours. Materials and methods: 51 patients with odontogenic tumours were subjected to preoperative MRI examinations. For tumours with liquid components, i.e. ameloblastomas and keratocystic odontogenic tumours (KCOTs), the signal intensity (SI) uniformity of their cystic components (US) was calculated and then their US values were compared. For tumours with solid components that had been examined using dynamic contrast-enhanced MRI (DCEMRI), their CI max (maximum contrast index), Tmax (the time when CImax occurred), CIpeak (CImax×0.90), Tpeak (the time when CIpeak occurred) and CI300 (i.e. the CI observed at 300 s after contrast medium injection) values were determined from CI curves. We then classified the odontogenic tumours according to their DCE-MRI parameters. Results: Significant differences between the US values of the ameloblastomas and KCOT were observed on T1 weighted images, T2 weighted images and short TI inversion recovery images. Depending on their DCE-MRI parameters, we classified the odontogenic tumours into the following five types: Type A, CIpeak > 2.0 and Tpeak <200 s; Type B, CIpeak <2.0 and Tpeak <200 s; Type C, CI 300 > 2.0 and Tmax <600 s; Type D, CI300 > 2.0 and Tmax > 600 s; Type E, CI300 <2.0 and Tmax > 600 s. Conclusion: Cystic component SI uniformity was found to be useful for differentiating between ameloblastomas and KCOT. However, the DCE-MRI parameters of odontogenic tumours, except for odontogenic fibromas and odontogenic myxomas, contributed little to their differential diagnosis.

Original languageEnglish
Article number20120265
JournalDentomaxillofacial Radiology
Volume42
Issue number5
DOIs
Publication statusPublished - May 2013

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Odontogenic Tumors
Ameloblastoma
Myxoma
Fibroma
Contrast Media
Neoplasms
Differential Diagnosis
Injections

Keywords

  • Ameloblastoma
  • Keratocystic odontogenic tumour
  • Magnetic resonance imaging
  • Odontogenic tumour

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Otorhinolaryngology
  • Dentistry(all)

Cite this

Diagnostic value of MRI for odontogenic tumours. / Fujita, Mariko; Matsuzaki, Hidenobu; Yanagi, Yoshinobu; Hara, M.; Katase, N.; Hisatomi, Miki; Unetsubo, T.; Konouchi, H.; Nagatsuka, Hitoshi; Asaumi, Jun-Ichi.

In: Dentomaxillofacial Radiology, Vol. 42, No. 5, 20120265, 05.2013.

Research output: Contribution to journalArticle

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abstract = "Objectives: To evaluate the diagnostic value of MRI for odontogenic tumours. Materials and methods: 51 patients with odontogenic tumours were subjected to preoperative MRI examinations. For tumours with liquid components, i.e. ameloblastomas and keratocystic odontogenic tumours (KCOTs), the signal intensity (SI) uniformity of their cystic components (US) was calculated and then their US values were compared. For tumours with solid components that had been examined using dynamic contrast-enhanced MRI (DCEMRI), their CI max (maximum contrast index), Tmax (the time when CImax occurred), CIpeak (CImax×0.90), Tpeak (the time when CIpeak occurred) and CI300 (i.e. the CI observed at 300 s after contrast medium injection) values were determined from CI curves. We then classified the odontogenic tumours according to their DCE-MRI parameters. Results: Significant differences between the US values of the ameloblastomas and KCOT were observed on T1 weighted images, T2 weighted images and short TI inversion recovery images. Depending on their DCE-MRI parameters, we classified the odontogenic tumours into the following five types: Type A, CIpeak > 2.0 and Tpeak <200 s; Type B, CIpeak <2.0 and Tpeak <200 s; Type C, CI 300 > 2.0 and Tmax <600 s; Type D, CI300 > 2.0 and Tmax > 600 s; Type E, CI300 <2.0 and Tmax > 600 s. Conclusion: Cystic component SI uniformity was found to be useful for differentiating between ameloblastomas and KCOT. However, the DCE-MRI parameters of odontogenic tumours, except for odontogenic fibromas and odontogenic myxomas, contributed little to their differential diagnosis.",
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author = "Mariko Fujita and Hidenobu Matsuzaki and Yoshinobu Yanagi and M. Hara and N. Katase and Miki Hisatomi and T. Unetsubo and H. Konouchi and Hitoshi Nagatsuka and Jun-Ichi Asaumi",
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AU - Fujita, Mariko

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AU - Hisatomi, Miki

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N2 - Objectives: To evaluate the diagnostic value of MRI for odontogenic tumours. Materials and methods: 51 patients with odontogenic tumours were subjected to preoperative MRI examinations. For tumours with liquid components, i.e. ameloblastomas and keratocystic odontogenic tumours (KCOTs), the signal intensity (SI) uniformity of their cystic components (US) was calculated and then their US values were compared. For tumours with solid components that had been examined using dynamic contrast-enhanced MRI (DCEMRI), their CI max (maximum contrast index), Tmax (the time when CImax occurred), CIpeak (CImax×0.90), Tpeak (the time when CIpeak occurred) and CI300 (i.e. the CI observed at 300 s after contrast medium injection) values were determined from CI curves. We then classified the odontogenic tumours according to their DCE-MRI parameters. Results: Significant differences between the US values of the ameloblastomas and KCOT were observed on T1 weighted images, T2 weighted images and short TI inversion recovery images. Depending on their DCE-MRI parameters, we classified the odontogenic tumours into the following five types: Type A, CIpeak > 2.0 and Tpeak <200 s; Type B, CIpeak <2.0 and Tpeak <200 s; Type C, CI 300 > 2.0 and Tmax <600 s; Type D, CI300 > 2.0 and Tmax > 600 s; Type E, CI300 <2.0 and Tmax > 600 s. Conclusion: Cystic component SI uniformity was found to be useful for differentiating between ameloblastomas and KCOT. However, the DCE-MRI parameters of odontogenic tumours, except for odontogenic fibromas and odontogenic myxomas, contributed little to their differential diagnosis.

AB - Objectives: To evaluate the diagnostic value of MRI for odontogenic tumours. Materials and methods: 51 patients with odontogenic tumours were subjected to preoperative MRI examinations. For tumours with liquid components, i.e. ameloblastomas and keratocystic odontogenic tumours (KCOTs), the signal intensity (SI) uniformity of their cystic components (US) was calculated and then their US values were compared. For tumours with solid components that had been examined using dynamic contrast-enhanced MRI (DCEMRI), their CI max (maximum contrast index), Tmax (the time when CImax occurred), CIpeak (CImax×0.90), Tpeak (the time when CIpeak occurred) and CI300 (i.e. the CI observed at 300 s after contrast medium injection) values were determined from CI curves. We then classified the odontogenic tumours according to their DCE-MRI parameters. Results: Significant differences between the US values of the ameloblastomas and KCOT were observed on T1 weighted images, T2 weighted images and short TI inversion recovery images. Depending on their DCE-MRI parameters, we classified the odontogenic tumours into the following five types: Type A, CIpeak > 2.0 and Tpeak <200 s; Type B, CIpeak <2.0 and Tpeak <200 s; Type C, CI 300 > 2.0 and Tmax <600 s; Type D, CI300 > 2.0 and Tmax > 600 s; Type E, CI300 <2.0 and Tmax > 600 s. Conclusion: Cystic component SI uniformity was found to be useful for differentiating between ameloblastomas and KCOT. However, the DCE-MRI parameters of odontogenic tumours, except for odontogenic fibromas and odontogenic myxomas, contributed little to their differential diagnosis.

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