Diagnostic value of MR imaging for dentigerous cysts

Hironobu Konouchi, Jun-Ichi Asaumi, Yoshinobu Yanagi, Miki Hisatomi, Emiko Saito Arita, Plauto Christopher Aranha Watanabe, Jun Murakami, Teruhisa Unetsubo, Mariko Fujita, Shunsuke Okada, Hidenobu Matsuzaki, Toshihiko Takenobu, Toru Wakasa

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Objectives It is known that the magnetic resonance (MR)imaging features of dentigerous cysts (DCs) are the same as those of other cysts. The cavities of DCs generally show low signal intensity (SI) on T1-weighted imaging (T1WI). However, in our experience, DCs often show high SI on T1WI, rendering them difficult to distinguish from keratocystic odontogenic tumors (KCOTs). In this study, we evaluated seven cases of DC and 23 cases of KCOT to assess whether MR imaging can provide additional information for the differential diagnosis of DC and KCOT. Methods Two trials were evaluated. The first trial was an analysis of the cystic cavity SI on T1WI. To compare the SI between patients, we performed T1WI with contrast (T1c). The second trial analyzed the SI uniformity (UR) on T1WI, T2-weighted imaging (T2WI), and short inversion time inversion recovery (STIR) images of the cystic cavity, because it has been reported that an MR imaging feature of KCOT is heterogeneous SI. Statistical analyses were performed using the Mann-Whitney U test and a receiver operating characteristic (ROC) curve. Results The T1c values of DCs were significantly higher than those for KCOTs. The UR values on T1WI and STIR images were significantly higher for DCs than for KCOTs. The T1c cutoff values (0.66 and 0.84) and UR cutoff values for T1WI (82.1 %) and STIR images (79.8 %) were determined from the ROC analyses. Conclusions T1c and UR values provide useful additional information for the differential diagnosis of DC and KCOT.

Original languageEnglish
Pages (from-to)13-19
Number of pages7
JournalOral Radiology
Volume30
Issue number1
DOIs
Publication statusPublished - 2014

Fingerprint

Dentigerous Cyst
Odontogenic Tumors
Magnetic Resonance Imaging
ROC Curve
Differential Diagnosis
Nonparametric Statistics
Cysts

Keywords

  • Cystic cavity
  • Dentigerous cyst
  • Keratocystic odontogenic tumor
  • MR imaging
  • Uniformity

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Dentistry (miscellaneous)

Cite this

Diagnostic value of MR imaging for dentigerous cysts. / Konouchi, Hironobu; Asaumi, Jun-Ichi; Yanagi, Yoshinobu; Hisatomi, Miki; Arita, Emiko Saito; Watanabe, Plauto Christopher Aranha; Murakami, Jun; Unetsubo, Teruhisa; Fujita, Mariko; Okada, Shunsuke; Matsuzaki, Hidenobu; Takenobu, Toshihiko; Wakasa, Toru.

In: Oral Radiology, Vol. 30, No. 1, 2014, p. 13-19.

Research output: Contribution to journalArticle

Konouchi, H, Asaumi, J-I, Yanagi, Y, Hisatomi, M, Arita, ES, Watanabe, PCA, Murakami, J, Unetsubo, T, Fujita, M, Okada, S, Matsuzaki, H, Takenobu, T & Wakasa, T 2014, 'Diagnostic value of MR imaging for dentigerous cysts', Oral Radiology, vol. 30, no. 1, pp. 13-19. https://doi.org/10.1007/s11282-013-0128-2
Konouchi, Hironobu ; Asaumi, Jun-Ichi ; Yanagi, Yoshinobu ; Hisatomi, Miki ; Arita, Emiko Saito ; Watanabe, Plauto Christopher Aranha ; Murakami, Jun ; Unetsubo, Teruhisa ; Fujita, Mariko ; Okada, Shunsuke ; Matsuzaki, Hidenobu ; Takenobu, Toshihiko ; Wakasa, Toru. / Diagnostic value of MR imaging for dentigerous cysts. In: Oral Radiology. 2014 ; Vol. 30, No. 1. pp. 13-19.
@article{d1ada49fe64845bc81a3081884bf5da2,
title = "Diagnostic value of MR imaging for dentigerous cysts",
abstract = "Objectives It is known that the magnetic resonance (MR)imaging features of dentigerous cysts (DCs) are the same as those of other cysts. The cavities of DCs generally show low signal intensity (SI) on T1-weighted imaging (T1WI). However, in our experience, DCs often show high SI on T1WI, rendering them difficult to distinguish from keratocystic odontogenic tumors (KCOTs). In this study, we evaluated seven cases of DC and 23 cases of KCOT to assess whether MR imaging can provide additional information for the differential diagnosis of DC and KCOT. Methods Two trials were evaluated. The first trial was an analysis of the cystic cavity SI on T1WI. To compare the SI between patients, we performed T1WI with contrast (T1c). The second trial analyzed the SI uniformity (UR) on T1WI, T2-weighted imaging (T2WI), and short inversion time inversion recovery (STIR) images of the cystic cavity, because it has been reported that an MR imaging feature of KCOT is heterogeneous SI. Statistical analyses were performed using the Mann-Whitney U test and a receiver operating characteristic (ROC) curve. Results The T1c values of DCs were significantly higher than those for KCOTs. The UR values on T1WI and STIR images were significantly higher for DCs than for KCOTs. The T1c cutoff values (0.66 and 0.84) and UR cutoff values for T1WI (82.1 {\%}) and STIR images (79.8 {\%}) were determined from the ROC analyses. Conclusions T1c and UR values provide useful additional information for the differential diagnosis of DC and KCOT.",
keywords = "Cystic cavity, Dentigerous cyst, Keratocystic odontogenic tumor, MR imaging, Uniformity",
author = "Hironobu Konouchi and Jun-Ichi Asaumi and Yoshinobu Yanagi and Miki Hisatomi and Arita, {Emiko Saito} and Watanabe, {Plauto Christopher Aranha} and Jun Murakami and Teruhisa Unetsubo and Mariko Fujita and Shunsuke Okada and Hidenobu Matsuzaki and Toshihiko Takenobu and Toru Wakasa",
year = "2014",
doi = "10.1007/s11282-013-0128-2",
language = "English",
volume = "30",
pages = "13--19",
journal = "Oral Radiology",
issn = "0911-6028",
publisher = "Springer Japan",
number = "1",

}

TY - JOUR

T1 - Diagnostic value of MR imaging for dentigerous cysts

AU - Konouchi, Hironobu

AU - Asaumi, Jun-Ichi

AU - Yanagi, Yoshinobu

AU - Hisatomi, Miki

AU - Arita, Emiko Saito

AU - Watanabe, Plauto Christopher Aranha

AU - Murakami, Jun

AU - Unetsubo, Teruhisa

AU - Fujita, Mariko

AU - Okada, Shunsuke

AU - Matsuzaki, Hidenobu

AU - Takenobu, Toshihiko

AU - Wakasa, Toru

PY - 2014

Y1 - 2014

N2 - Objectives It is known that the magnetic resonance (MR)imaging features of dentigerous cysts (DCs) are the same as those of other cysts. The cavities of DCs generally show low signal intensity (SI) on T1-weighted imaging (T1WI). However, in our experience, DCs often show high SI on T1WI, rendering them difficult to distinguish from keratocystic odontogenic tumors (KCOTs). In this study, we evaluated seven cases of DC and 23 cases of KCOT to assess whether MR imaging can provide additional information for the differential diagnosis of DC and KCOT. Methods Two trials were evaluated. The first trial was an analysis of the cystic cavity SI on T1WI. To compare the SI between patients, we performed T1WI with contrast (T1c). The second trial analyzed the SI uniformity (UR) on T1WI, T2-weighted imaging (T2WI), and short inversion time inversion recovery (STIR) images of the cystic cavity, because it has been reported that an MR imaging feature of KCOT is heterogeneous SI. Statistical analyses were performed using the Mann-Whitney U test and a receiver operating characteristic (ROC) curve. Results The T1c values of DCs were significantly higher than those for KCOTs. The UR values on T1WI and STIR images were significantly higher for DCs than for KCOTs. The T1c cutoff values (0.66 and 0.84) and UR cutoff values for T1WI (82.1 %) and STIR images (79.8 %) were determined from the ROC analyses. Conclusions T1c and UR values provide useful additional information for the differential diagnosis of DC and KCOT.

AB - Objectives It is known that the magnetic resonance (MR)imaging features of dentigerous cysts (DCs) are the same as those of other cysts. The cavities of DCs generally show low signal intensity (SI) on T1-weighted imaging (T1WI). However, in our experience, DCs often show high SI on T1WI, rendering them difficult to distinguish from keratocystic odontogenic tumors (KCOTs). In this study, we evaluated seven cases of DC and 23 cases of KCOT to assess whether MR imaging can provide additional information for the differential diagnosis of DC and KCOT. Methods Two trials were evaluated. The first trial was an analysis of the cystic cavity SI on T1WI. To compare the SI between patients, we performed T1WI with contrast (T1c). The second trial analyzed the SI uniformity (UR) on T1WI, T2-weighted imaging (T2WI), and short inversion time inversion recovery (STIR) images of the cystic cavity, because it has been reported that an MR imaging feature of KCOT is heterogeneous SI. Statistical analyses were performed using the Mann-Whitney U test and a receiver operating characteristic (ROC) curve. Results The T1c values of DCs were significantly higher than those for KCOTs. The UR values on T1WI and STIR images were significantly higher for DCs than for KCOTs. The T1c cutoff values (0.66 and 0.84) and UR cutoff values for T1WI (82.1 %) and STIR images (79.8 %) were determined from the ROC analyses. Conclusions T1c and UR values provide useful additional information for the differential diagnosis of DC and KCOT.

KW - Cystic cavity

KW - Dentigerous cyst

KW - Keratocystic odontogenic tumor

KW - MR imaging

KW - Uniformity

UR - http://www.scopus.com/inward/record.url?scp=84895493150&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84895493150&partnerID=8YFLogxK

U2 - 10.1007/s11282-013-0128-2

DO - 10.1007/s11282-013-0128-2

M3 - Article

AN - SCOPUS:84895493150

VL - 30

SP - 13

EP - 19

JO - Oral Radiology

JF - Oral Radiology

SN - 0911-6028

IS - 1

ER -