Abstract
For precise identification of an epileptic focus in mesial temporal lobe epilepsy (MTLE), various techniques, including neuroimaging, are employed. We performed topographic and spike dipole analyses to investigate the correlation between surface electroencephalogram (EEG) and the location of the lesion in 10 patients with MTLE. Six patients with interictal epileptic spikes on EEG were analyzed by the dipole localization method using CDT 1000 (Central Electronics Company, Tokyo). The location of the spike dipoles were compared with the location of abnormal lesions revealed by magnetic resonance imaging (MRI). In all 10 cases, EEG topography was also performed to determine an abnormal lesion from the EEG background activity. In six cases, spike dipoles were located at the mesial temporal lobe, which corresponded to the MRI lesion. In seven of the 10 cases, EEG topography revealed the deviation of the delta band to one side in the frontal to anterior temporal area. In these seven cases, the laterality of the delta band deviation coincided with the site of the MRI abnormality. In one case, a topographic abnormality was provoked after sleep deprivation. We conclude that EEG analysis combined with MRI is useful for the evaluation of the epileptic focus in MTLE. Topographic analysis of basic EEG was considered to be beneficial especially in MTLE, in which epileptic spikes were rare.
| Original language | English |
|---|---|
| Pages (from-to) | 1-9 |
| Number of pages | 9 |
| Journal | Journal of Epilepsy |
| Volume | 11 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jan 1998 |
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Keywords
- Dipole analysis
- EEG topography
- Epileptic focus.
- Mesial temporal lobe epilepsy
- Volumetry
ASJC Scopus subject areas
- Clinical Neurology
- Neuroscience(all)
Cite this
Diagnostic value of EEG analysis of epileptic focus in mesial temporal lobe epilepsy (MTLE). / Yoshinaga, Harumi; Ohno, Shigeru; Nakahori, Tomoyuki; Oka, Eiji; Ohtahara, Shunsuke; Tanaka, Akio; Miyamoto, Keiichi.
In: Journal of Epilepsy, Vol. 11, No. 1, 01.1998, p. 1-9.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Diagnostic value of EEG analysis of epileptic focus in mesial temporal lobe epilepsy (MTLE)
AU - Yoshinaga, Harumi
AU - Ohno, Shigeru
AU - Nakahori, Tomoyuki
AU - Oka, Eiji
AU - Ohtahara, Shunsuke
AU - Tanaka, Akio
AU - Miyamoto, Keiichi
PY - 1998/1
Y1 - 1998/1
N2 - For precise identification of an epileptic focus in mesial temporal lobe epilepsy (MTLE), various techniques, including neuroimaging, are employed. We performed topographic and spike dipole analyses to investigate the correlation between surface electroencephalogram (EEG) and the location of the lesion in 10 patients with MTLE. Six patients with interictal epileptic spikes on EEG were analyzed by the dipole localization method using CDT 1000 (Central Electronics Company, Tokyo). The location of the spike dipoles were compared with the location of abnormal lesions revealed by magnetic resonance imaging (MRI). In all 10 cases, EEG topography was also performed to determine an abnormal lesion from the EEG background activity. In six cases, spike dipoles were located at the mesial temporal lobe, which corresponded to the MRI lesion. In seven of the 10 cases, EEG topography revealed the deviation of the delta band to one side in the frontal to anterior temporal area. In these seven cases, the laterality of the delta band deviation coincided with the site of the MRI abnormality. In one case, a topographic abnormality was provoked after sleep deprivation. We conclude that EEG analysis combined with MRI is useful for the evaluation of the epileptic focus in MTLE. Topographic analysis of basic EEG was considered to be beneficial especially in MTLE, in which epileptic spikes were rare.
AB - For precise identification of an epileptic focus in mesial temporal lobe epilepsy (MTLE), various techniques, including neuroimaging, are employed. We performed topographic and spike dipole analyses to investigate the correlation between surface electroencephalogram (EEG) and the location of the lesion in 10 patients with MTLE. Six patients with interictal epileptic spikes on EEG were analyzed by the dipole localization method using CDT 1000 (Central Electronics Company, Tokyo). The location of the spike dipoles were compared with the location of abnormal lesions revealed by magnetic resonance imaging (MRI). In all 10 cases, EEG topography was also performed to determine an abnormal lesion from the EEG background activity. In six cases, spike dipoles were located at the mesial temporal lobe, which corresponded to the MRI lesion. In seven of the 10 cases, EEG topography revealed the deviation of the delta band to one side in the frontal to anterior temporal area. In these seven cases, the laterality of the delta band deviation coincided with the site of the MRI abnormality. In one case, a topographic abnormality was provoked after sleep deprivation. We conclude that EEG analysis combined with MRI is useful for the evaluation of the epileptic focus in MTLE. Topographic analysis of basic EEG was considered to be beneficial especially in MTLE, in which epileptic spikes were rare.
KW - Dipole analysis
KW - EEG topography
KW - Epileptic focus.
KW - Mesial temporal lobe epilepsy
KW - Volumetry
UR - http://www.scopus.com/inward/record.url?scp=0031910657&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0031910657&partnerID=8YFLogxK
U2 - 10.1016/S0896-6974(97)00104-7
DO - 10.1016/S0896-6974(97)00104-7
M3 - Article
AN - SCOPUS:0031910657
VL - 11
SP - 1
EP - 9
JO - Epilepsy Research
JF - Epilepsy Research
SN - 0920-1211
IS - 1
ER -