Diagnostic validity of high-density barium sulfate in gastric cancer screening

Follow-up of Screenees by Record Linkage with the Osaka Cancer registry

Kenyu Yamamoto, Hideo Yamazaki, Chikazumi Kuroda, Tsugio Kubo, Akira Oshima, Toshizo Katsuda, Tadao Kuwano, Yoshihiro Takeda

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Background: The use of high-density barium sulfate was recommended by the Japan Society of Gastroenterological Cancer Screening (JSGCS) in 2004. We evaluated the diagnostic validity of gastric cancer screening that used high-density barium sulfate. Methods: The study subjects were 171 833 residents of Osaka, Japan who underwent gastric cancer screening tests at the Osaka Cancer Prevention and Detection Center during the period from 1 January 2000 through 31 December 2001. Screening was conducted using either high-density barium sulfate (n = 48 336) or moderate-density barium sulfate (n = 123 497). The subjects were followed up and their medical records were linked to those of the Osaka Cancer Registry through 31 December 2002. The results of follow-up during 1 year were defined as the gold standard, and test performance values were calculated. Results: The sensitivity and specificity of the screening test using moderate-density barium sulfate were 92.3% and 91.0%, respectively, while the sensitivity and specificity of the high-density barium test were 91.8% and 91.4%, respectively. The results of area under receiver-operating-characteristic (ROC) curve analysis revealed no significant difference between the 2 screening tests. Conclusions: Screening tests using high- and moderate-density barium sulfate had similar validity, as determined by sensitivity, specificity, and ROC curve analysis.

Original languageEnglish
Pages (from-to)287-294
Number of pages8
JournalJournal of Epidemiology
Volume20
Issue number4
DOIs
Publication statusPublished - 2010

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Barium Sulfate
Early Detection of Cancer
Stomach Neoplasms
Registries
Neoplasms
Sensitivity and Specificity
ROC Curve
Japan
Barium
Medical Records

Keywords

  • Area under ROC curve (AUC) analysis
  • Barium sulfate
  • Gastric cancer screening
  • Sensitivity
  • Specificity

ASJC Scopus subject areas

  • Epidemiology
  • Medicine(all)

Cite this

Diagnostic validity of high-density barium sulfate in gastric cancer screening : Follow-up of Screenees by Record Linkage with the Osaka Cancer registry. / Yamamoto, Kenyu; Yamazaki, Hideo; Kuroda, Chikazumi; Kubo, Tsugio; Oshima, Akira; Katsuda, Toshizo; Kuwano, Tadao; Takeda, Yoshihiro.

In: Journal of Epidemiology, Vol. 20, No. 4, 2010, p. 287-294.

Research output: Contribution to journalArticle

Yamamoto, Kenyu ; Yamazaki, Hideo ; Kuroda, Chikazumi ; Kubo, Tsugio ; Oshima, Akira ; Katsuda, Toshizo ; Kuwano, Tadao ; Takeda, Yoshihiro. / Diagnostic validity of high-density barium sulfate in gastric cancer screening : Follow-up of Screenees by Record Linkage with the Osaka Cancer registry. In: Journal of Epidemiology. 2010 ; Vol. 20, No. 4. pp. 287-294.
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