Diagnostic ability of convex-arrayed endoscopic ultrasonography for major vascular invasion in pancreatic cancer

Yuki Fujii, Kazuyuki Matsumoto, Hironari Kato, Yosuke Saragai, Saimon Takada, Sho Mizukawa, Shinichiro Muro, Daisuke Uchida, Takeshi Tomoda, Shigeru Horiguchi, Noriyuki Tanaka, Hiroyuki Okada

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background/Aims: This study aimed to examine the diagnostic ability of endoscopic ultrasonography (EUS) for major vascular invasion in pancreatic cancer and to evaluate the relationship between EUS findings and pathological distance. Methods: In total, 57 consecutive patients who underwent EUS for pancreatic cancer before surgery were retrospectively reviewed. EUS image findings were divided into four types according to the relationship between the tumor and major vessel (types 1 and 2: invasion, types 3 and 4: non-invasion). We also compared the EUS findings and pathologically measured distances between the tumors and evaluated vessels. Results: The sensitivity, specificity, and accuracy of EUS diagnosis for vascular invasion were 89%, 92%, and 91%, respectively, in the veins and 83%, 94%, and 93%, respectively, in the arteries. The pathologically evaluated distances of cases with type 2 EUS findings were significantly shorter than those of cases with type 3 EUS findings in both the major veins (median [interquartile range], 96 [0–742] µm vs. 2,833 [1,076–5,694] µm, p=0.012) and arteries (623 [0–854] µm vs. 3,097 [1,396–6,000] µm, p=0.0061). All cases with a distance of ≥1,000 µm between the tumors and main vessels were correctly diagnosed. Conclusions: Tumors at a distance ≥1,000 µm from the main vessels were correctly diagnosed by EUS.

Original languageEnglish
Pages (from-to)479-485
Number of pages7
JournalClinical Endoscopy
Volume52
Issue number5
DOIs
Publication statusPublished - Jan 1 2019

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Endosonography
Pancreatic Neoplasms
Blood Vessels
Veins
Neoplasms
Arteries
Sensitivity and Specificity

Keywords

  • Endoscopic ultrasonography
  • Pancreatic cancer
  • Pathological distance
  • Staging
  • Vascular invasion

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Radiology Nuclear Medicine and imaging
  • Gastroenterology

Cite this

Diagnostic ability of convex-arrayed endoscopic ultrasonography for major vascular invasion in pancreatic cancer. / Fujii, Yuki; Matsumoto, Kazuyuki; Kato, Hironari; Saragai, Yosuke; Takada, Saimon; Mizukawa, Sho; Muro, Shinichiro; Uchida, Daisuke; Tomoda, Takeshi; Horiguchi, Shigeru; Tanaka, Noriyuki; Okada, Hiroyuki.

In: Clinical Endoscopy, Vol. 52, No. 5, 01.01.2019, p. 479-485.

Research output: Contribution to journalArticle

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AU - Takada, Saimon

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AU - Muro, Shinichiro

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