Diagnosis of pheochromocytoma by 131I-MIBG scintigraphy

N. Miyanaga, K. Hattori, H. Shiraiwa, S. Hinotsu, R. Nemoto, K. Koiso, T. Takeda, N. Ishikawa

Research output: Contribution to journalArticle

Abstract

Between February, 1984, and June, 1988, 131I-metaiodobenzylguanidine (131I-MIBG) scintigraphy was performed on 48 patients with suspected pheochromocytoma at our hospital. Whole body image and/or spot images were obtained 24, 48 and 72 hours after injection of 0.5 mCi of 131I-MIBG. In 10 of 12 patients with surgically proven pheochromocytoma, 131I-MIBG was accumulated in the primary and metastatic tumor. 131I-MIBG scintigraphy was negative in 2 patients. One case of renal cyst had the accumulation of 131I-MIBG but the disease could be confirmed. By 131I-MIBG scintigraphy sensitivity was 83% (10/12), and specificity was 97% (35/36). Heart intensity was much higher in patients with nonpheochromocytoma than those with pheochromocytoma. Thus 131I-MIBG scintigraphy proved to be safe, non-invasive and specific in the diagnosis of pheochromocytoma.

Original languageEnglish
Pages (from-to)105-108
Number of pages4
JournalActa Urologica Japonica
Volume36
Issue number2
Publication statusPublished - Feb 1990
Externally publishedYes

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Pheochromocytoma
Radionuclide Imaging
Body Image
Cysts
Kidney
Injections
Neoplasms

ASJC Scopus subject areas

  • Urology

Cite this

Miyanaga, N., Hattori, K., Shiraiwa, H., Hinotsu, S., Nemoto, R., Koiso, K., ... Ishikawa, N. (1990). Diagnosis of pheochromocytoma by 131I-MIBG scintigraphy. Acta Urologica Japonica, 36(2), 105-108.

Diagnosis of pheochromocytoma by 131I-MIBG scintigraphy. / Miyanaga, N.; Hattori, K.; Shiraiwa, H.; Hinotsu, S.; Nemoto, R.; Koiso, K.; Takeda, T.; Ishikawa, N.

In: Acta Urologica Japonica, Vol. 36, No. 2, 02.1990, p. 105-108.

Research output: Contribution to journalArticle

Miyanaga, N, Hattori, K, Shiraiwa, H, Hinotsu, S, Nemoto, R, Koiso, K, Takeda, T & Ishikawa, N 1990, 'Diagnosis of pheochromocytoma by 131I-MIBG scintigraphy', Acta Urologica Japonica, vol. 36, no. 2, pp. 105-108.
Miyanaga N, Hattori K, Shiraiwa H, Hinotsu S, Nemoto R, Koiso K et al. Diagnosis of pheochromocytoma by 131I-MIBG scintigraphy. Acta Urologica Japonica. 1990 Feb;36(2):105-108.
Miyanaga, N. ; Hattori, K. ; Shiraiwa, H. ; Hinotsu, S. ; Nemoto, R. ; Koiso, K. ; Takeda, T. ; Ishikawa, N. / Diagnosis of pheochromocytoma by 131I-MIBG scintigraphy. In: Acta Urologica Japonica. 1990 ; Vol. 36, No. 2. pp. 105-108.
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abstract = "Between February, 1984, and June, 1988, 131I-metaiodobenzylguanidine (131I-MIBG) scintigraphy was performed on 48 patients with suspected pheochromocytoma at our hospital. Whole body image and/or spot images were obtained 24, 48 and 72 hours after injection of 0.5 mCi of 131I-MIBG. In 10 of 12 patients with surgically proven pheochromocytoma, 131I-MIBG was accumulated in the primary and metastatic tumor. 131I-MIBG scintigraphy was negative in 2 patients. One case of renal cyst had the accumulation of 131I-MIBG but the disease could be confirmed. By 131I-MIBG scintigraphy sensitivity was 83{\%} (10/12), and specificity was 97{\%} (35/36). Heart intensity was much higher in patients with nonpheochromocytoma than those with pheochromocytoma. Thus 131I-MIBG scintigraphy proved to be safe, non-invasive and specific in the diagnosis of pheochromocytoma.",
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AU - Hattori, K.

AU - Shiraiwa, H.

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AU - Nemoto, R.

AU - Koiso, K.

AU - Takeda, T.

AU - Ishikawa, N.

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AB - Between February, 1984, and June, 1988, 131I-metaiodobenzylguanidine (131I-MIBG) scintigraphy was performed on 48 patients with suspected pheochromocytoma at our hospital. Whole body image and/or spot images were obtained 24, 48 and 72 hours after injection of 0.5 mCi of 131I-MIBG. In 10 of 12 patients with surgically proven pheochromocytoma, 131I-MIBG was accumulated in the primary and metastatic tumor. 131I-MIBG scintigraphy was negative in 2 patients. One case of renal cyst had the accumulation of 131I-MIBG but the disease could be confirmed. By 131I-MIBG scintigraphy sensitivity was 83% (10/12), and specificity was 97% (35/36). Heart intensity was much higher in patients with nonpheochromocytoma than those with pheochromocytoma. Thus 131I-MIBG scintigraphy proved to be safe, non-invasive and specific in the diagnosis of pheochromocytoma.

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