Abstract
Optically active 1,1,2-trifluoro- or 1,2-difluoroallylic alcohols were prepared via a lipase-catalyzed reaction and their absolute configuration was determined by an X-ray crystallographic analysis of the corresponding ferrocene ester along with the refined Mosher method (the Kusumi-Ohtani method).
Original language | English |
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Pages (from-to) | 7889-7892 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 41 |
Issue number | 41 |
DOIs | |
Publication status | Published - Oct 7 2000 |
Keywords
- Absolute configuration determination
- Fluorinated allylic alcohol
- Refined Mosher method
- X-ray crystallographic analysis
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry