Detection of TIMI-3 flow before mechanical reperfusion with ultrasonic tissue characterization in patients with anterior wall acute myocardial infarction

Katsuomi Iwakura, Hiroshi Itoh, Shigeo Kawano, Atsushi Okamura, Katsuaki Asano, Tadashi Kuroda, Koji Tanaka, Tohru Masuyama, Masatsugu Hori, Kenshi Fujii

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Background - Spontaneous coronary reperfusion with TIMI-3 flow is associated with favorable clinical outcomes in patients with acute myocardial infarction (AMI). We investigated the ability of analyzing cardiac cycle-dependent variation of myocardial integrated backscatter (IBS) for predicting spontaneous reperfusion in anterior AMI. Methods and Results - We recorded IBS images on admission in 104 patients with first anterior wall AMI and subsequently performed coronary angiography and coronary intervention. We measured the cyclic variation of IBS within the infarct zone and expressed its magnitude as phase-corrected magnitude (PCM) by giving positive and negative values when it showed synchronous and asynchronous contraction, respectively. Twenty-three patients showing TIMI-3 flow at the initial coronary angiography had smaller peak creatine kinase value than 57 patients with initial TIMI-0/1 flow (864±961 versus 2358±1757 IU/L; P=0.0002) and better percent wall thickening within risk area (36.1±15.1%) than those with TIMI-2 (16.7±12.8%, P

Original languageEnglish
Pages (from-to)3159-3164
Number of pages6
JournalCirculation
Volume107
Issue number25
DOIs
Publication statusPublished - Jul 1 2003
Externally publishedYes

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Anterior Wall Myocardial Infarction
Ultrasonics
Reperfusion
Coronary Angiography
Myocardial Infarction
Myocardial Reperfusion
Creatine Kinase

Keywords

  • Echocardiography
  • Myocardial infarction
  • Reperfusion

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Detection of TIMI-3 flow before mechanical reperfusion with ultrasonic tissue characterization in patients with anterior wall acute myocardial infarction. / Iwakura, Katsuomi; Itoh, Hiroshi; Kawano, Shigeo; Okamura, Atsushi; Asano, Katsuaki; Kuroda, Tadashi; Tanaka, Koji; Masuyama, Tohru; Hori, Masatsugu; Fujii, Kenshi.

In: Circulation, Vol. 107, No. 25, 01.07.2003, p. 3159-3164.

Research output: Contribution to journalArticle

Iwakura, Katsuomi ; Itoh, Hiroshi ; Kawano, Shigeo ; Okamura, Atsushi ; Asano, Katsuaki ; Kuroda, Tadashi ; Tanaka, Koji ; Masuyama, Tohru ; Hori, Masatsugu ; Fujii, Kenshi. / Detection of TIMI-3 flow before mechanical reperfusion with ultrasonic tissue characterization in patients with anterior wall acute myocardial infarction. In: Circulation. 2003 ; Vol. 107, No. 25. pp. 3159-3164.
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AU - Kuroda, Tadashi

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AU - Fujii, Kenshi

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