Detection of human papillomavirus type 6f genome in nasal papillomatosis

H. Ogura, T. Kawakami, T. Fujiwara, A. Sakai, R. Saito, S. Watanabe, Y. Masuda, Y. Yabe

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

Five cases of nasal papillomatosis were studied clinicopathologically and virologically. In a case of recurrent papillomatosis of non-inverted type located on the nasal septum, human papilloma-virus (HPV) DNA was detected by dot blot hybridization with an RNA cocktail probe of mucosal HPVs. In Southern blot hybridization, the DNA hybridized with that of HPV types 6 and 11 but not with those of types 16 and 18. Its restriction endonuclease-cleavage patterns corresponded well to those of HPV type 6f. These results suggested that HPV type 6 would also be associated with nasal non-inverted papillomatosis.

Original languageEnglish
Pages (from-to)115-119
Number of pages5
JournalActa Oto-Laryngologica
Volume112
Issue number1
DOIs
Publication statusPublished - 1992
Externally publishedYes

Keywords

  • Dot blot hybridization. Southern blot hybridization
  • HPV type 6
  • Koilocytosis
  • Papillomatosis of nasal cavity and paranasal sinus

ASJC Scopus subject areas

  • Otorhinolaryngology

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