Enzyme-linked immunosorbent assay of the core protein of hepatitis C virus (HCV) expressed in E. coli led to detection of the antibody against this virus in patients with chronic hepatitis. Some of the negative results obtained using a different viral protein became positive with this E. coli-expressed viral protein, and were also positive for the viral RNA. Thus, use of the core protein of HCV facilitates accurate detection of HCV infection.
|Number of pages||4|
|Journal||Japanese Journal of Cancer Research|
|Publication status||Published - Aug 1991|
- Hepatitis C virus
ASJC Scopus subject areas
- Cancer Research